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      Consumption of Alcoholic Beverages and the Prevalence of Metabolic Syndrome and Its Components

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          Abstract

          The relationship between alcohol consumption and the prevalence of metabolic syndrome is not consistent and may vary between populations, depending on age, sex, ethnicity, cultural traditions and lifestyle. We have hypothesized that moderate alcohol consumption will be associated with the lowest risk of the syndrome. The aim of the present study is to examine the relationship between the current consumption of alcohol and the prevalence of metabolic syndrome and its components. The research material includes data obtained from 12,285 men and women, in the age range of 37–66 years. Multiple logistic regression was used in the statistical analysis. Metabolic syndrome (MetS) was defined according to the International Diabetes Federation. In men, a current consumption of >30 g of alcohol/day was significantly associated with a higher risk of metabolic syndrome (OR = 1.73, 95% CI = 1.25–2.39), high blood pressure (OR = 2.76, 95% CI = 1.64–4.65), elevated glucose concentration (OR = 1.70, 95% CI = 1.24–2.32), and abdominal obesity (OR = 1.77; 95% CI = 1.07–2.92). In women, the consumption from 10.1 to 15.0 g of alcohol was associated only with a higher risk of abnormal glucose concentration (OR = 1.65; 95% CI = 1.14–2.38.) In both sexes, current alcohol consumption was associated with higher high-density lipoproteins (HDL)-cholesterol concentration ( p < 0.05). No relationship was found between alcohol consumption and triglyceride concentration. It is difficult to formulate unequivocal recommendations regarding alcohol intake in MetS prophylaxis due to its different association with particular MetS components. In order to explain the causal relationship between alcohol consumption and MetS and its components, prospective studies are necessary.

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          Sex and gender-related differences in alcohol use and its consequences: Contemporary knowledge and future research considerations.

          To review the contemporary evidence reflecting male/female differences in alcohol use and its consequences along with the biological (sex-related) and psycho-socio-cultural (gender-related) factors associated with those differences.
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            The effect of a reduction in alcohol consumption on blood pressure: a systematic review and meta-analysis

            Although it is well established that heavy alcohol consumption increases the risk of hypertension, little is known about the effect of a reduction of alcohol intake on blood pressure. We aimed to assess the effect of a reduction in alcohol consumption on change in blood pressure stratified by initial amount of alcohol consumption and sex in adults.
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              Alcohol consumption and risk of metabolic syndrome: a meta-analysis of prospective studies.

              Epidemiological evidence suggests that alcohol consumption is related to the incidence and development of metabolic syndrome. However, data on this issue are unstable and controversial. We conducted a meta-analysis to provide a quantitative assessment of the association between alcohol intake and risk of metabolic syndrome. We searched the Pubmed and Embase databases up to May 2013 to identify prospective cohort studies related to alcohol consumption and metabolic syndrome. Summary effect estimates with 95% confidence intervals (CI) were derived using a fixed or random effects model, depending on the heterogeneity of the included studies. Six prospective studies involving 28,862 participants with 3305 cases of metabolic syndrome were included in the meta-analysis. On the basis of the Newcastle Ottawa Scale system, 83.3% of the studies were identified as relatively high-quality. In our primary analysis, compared with nondrinker, very light drinker was associated with decreased risk of metabolic syndrome [pooled relative risk (RR) 0.86, 95% CI: 0.75-0.99, fixed-effect model] while heavy drinker was associated with increased risk of metabolic syndrome (pooled RR 1.84, 95% CI: 1.34-2.52, fixed-effect model). No indications of heterogeneity and publication bias were found in these two groups. Estimates of total effects were generally consistent in the sensitivity and stratification analyses. The present meta-analysis of prospective studies suggested that heavy alcohol consumption might be associated with an increased risk of metabolic syndrome while very light alcohol consumption seemed to be associated with a reduced risk of metabolic syndrome. Copyright © 2013. Published by Elsevier Ltd.
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                Author and article information

                Journal
                Nutrients
                Nutrients
                nutrients
                Nutrients
                MDPI
                2072-6643
                14 November 2019
                November 2019
                : 11
                : 11
                : 2764
                Affiliations
                [1 ]The Institute of Health Sciences, Medical College, Jan Kochanowski University (JKU), ul. Zeromskiego 5, 25-369 Kielce, Poland; dorota.koziel@ 123456ujk.edu.pl (D.K.); eciesla@ 123456ujk.edu.pl (E.C.); dorota.rebak@ 123456ujk.edu.pl (D.R.); mgluszekosuch@ 123456ujk.edu.pl (M.G.-O.)
                [2 ]The Institute of Medical Sciences, Medical College, JKU, ul. Zeromskiego 5, 25-369 Kielce, Poland; sgluszek@ 123456wp.pl
                Author notes
                [* ]Correspondence: edyta.suliga@ 123456ujk.edu.pl ; Tel.: +48-41-349-72-00; Fax: +48-41-349-72-01
                Author information
                https://orcid.org/0000-0003-3063-0380
                https://orcid.org/0000-0001-8114-1814
                https://orcid.org/0000-0001-7752-0459
                Article
                nutrients-11-02764
                10.3390/nu11112764
                6893759
                31739490
                5c93181b-9d96-46a1-ad14-a097cda63730
                © 2019 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 28 September 2019
                : 11 November 2019
                Categories
                Article

                Nutrition & Dietetics
                alcohol consumption,metabolic syndrome,men,women
                Nutrition & Dietetics
                alcohol consumption, metabolic syndrome, men, women

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