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Abstract
Traditional infection control measures in intensive care units (ICUs) have been directed
at limiting person to person spread of infection and improving care of invasive devices.
These measures often fail because they have little effect on patients' endogenous
flora, which is an important source of infection in ICUs. Improvements in the design
and aseptic care of invasive devices have helped to decrease the risk of progression
from colonization to infection in individual patients. Interest is growing also in
use of selective decontamination to decrease ICU infection rates. Despite these advances,
basic hygiene and appropriate, prospectively monitored use of antibiotics remain essential
components of ICU care.