Generalized pustular psoriasis (von Zumbusch) <sup>☆</sup>

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Abstract

Generalized pustular psoriasis (von Zumbusch) is a rare and acute eruption characterized by multiple sterile pustules over an erythematous and edematous background, eventually associated with psoriasis vulgaris. Classically, it manifests as a potentially severe systemic picture and demands prompt diagnosis and intervention. The duration of each flare-up and intervals between the pustular episodes is extremely variable. Recently, genetic abnormalities have been identified mainly in the familial and early variants of this disease. The therapeutic arsenal is limited; however, new drugs being evaluated aim to control both pustular flare-ups and disease recurrences.

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Author and article information

Contributors

André Luís da Silva Hirayama

Journal

Journal ID (nlm-ta): An Bras Dermatol

Journal ID (iso-abbrev): An Bras Dermatol

Title: Anais Brasileiros de Dermatologia

Publisher: Sociedade Brasileira de Dermatologia

ISSN (Print): 0365-0596

ISSN (Electronic): 1806-4841

Publication date PMC-release: 24 November 2021

Publication date (Print): Jan-Feb 2022

Publication date (Electronic): 24 November 2021

Volume: 97

Issue: 1

Pages: 63-74

Affiliations

[a ]Department of Dermatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil

[b ]Discipline of Dermatology, Faculdade de Ciências Médicas, Unicamp, Campinas, SP, Brazil

Author notes

[* ]Corresponding author. xkrandre1979@ 123456yahoo.com.br

Article

Publisher Item ID: S0365-0596(21)00275-0

DOI: 10.1016/j.abd.2021.05.011

PMC ID: 8799844

PubMed ID: 34838431

SO-VID: 4a52731e-0e27-4c66-a5b3-3740130cbc31

License:

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

History

Date received : 13 March 2021

Date accepted : 4 May 2021

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