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      Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill Patients : The BaSICS Randomized Clinical Trial

      1 , 2 , 2 , 3 , 2 , 4 , 2 , 5 , 2 , 6 , 7 , 8 , 9 , 2 , 10 , 11 , 12 , 13 , 14 , 2 , 15 , 16 , 2 , 17 , 2 , 18 , 10 , 19 , 20 , 21 , 1 , 1 , 1 , 1 , 1 , 2 , 10 , 2 , 22 , 23 , 1 , 24 , 1 , 2 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , 25 , BaSICS investigators and the BRICNet members
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      American Medical Association (AMA)

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          Proportional hazards tests and diagnostics based on weighted residuals

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            The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure: On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine (see contributors to the project in the appendix)

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              Notice

              SECTION I: USE OF THE CLINICAL PRACTICE GUIDELINE This Clinical Practice Guideline document is based upon the best information available as of February 2011. It is designed to provide information and assist decision-making. It is not intended to define a standard of care, and should not be construed as one, nor should it be interpreted as prescribing an exclusive course of management. Variations in practice will inevitably and appropriately occur when clinicians take into account the needs of individual patients, available resources, and limitations unique to an institution or type of practice. Every health-care professional making use of these recommendations is responsible for evaluating the appropriateness of applying them in the setting of any particular clinical situation. The recommendations for research contained within this document are general and do not imply a specific protocol. SECTION II: DISCLOSURE Kidney Disease: Improving Global Outcomes (KDIGO) makes every effort to avoid any actual or reasonably perceived conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the Work Group. All members of the Work Group are required to complete, sign, and submit a disclosure and attestation form showing all such relationships that might be perceived or actual conflicts of interest. This document is updated annually and information is adjusted accordingly. All reported information is published in its entirety at the end of this document in the Work Group members' Biographical and Disclosure Information section, and is kept on file at the National Kidney Foundation (NKF), Managing Agent for KDIGO.
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                Author and article information

                Journal
                JAMA
                JAMA
                American Medical Association (AMA)
                0098-7484
                August 10 2021
                Affiliations
                [1 ]HCor Research Institute, São Paulo, Brazil
                [2 ]Brazilian Research in Intensive Care Network, São Paulo, Brazil
                [3 ]Department of Anesthesiology, Pain and Intensive Care, Universidade Federal de São Paulo, São Paulo, Brazil
                [4 ]Instituto de Cardiologia do Distrito Federal, Brasília, Brazil
                [5 ]Hospital SEPACO, São Paulo, Brazil
                [6 ]BP–A Beneficência Portuguesa de São Paulo, São Paulo, Brazil
                [7 ]Hospital Maternidade São José, Centro Universitário do Espírito Santo, Colatina, Brazil
                [8 ]Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil
                [9 ]Fundação Pio XII, Hospital de Câncer de Barretos, Barretos, Brazil
                [10 ]Hospital Israelita Albert Einstein, São Paulo, Brazil
                [11 ]Santa Casa de Misericórdia de São João Del Rei, São João Del Rei, Brazil
                [12 ]Hospital Ana Nery, Salvador, Brazil
                [13 ]Hospital São Francisco, Santa Casa de Porto Alegre, Porto Alegre, Brazil
                [14 ]Hospital Geral Clériston Andrade, Feira de Santana, Brazil
                [15 ]Hospital Santa Rita, Santa Casa de Porto Alegre, Porto Alegre, Brazil
                [16 ]Hospital da Luz, São Paulo, Brazil
                [17 ]Hospital Nereu Ramos, Florianópolis, Brazil
                [18 ]Hospital Universitário Regional do Norte do Paraná, Universidade Estadual de Londrina, Londrina, Brazil
                [19 ]Hospital Paulistano, São Paulo, Brazil
                [20 ]Hospital do Servidor Público Estadual, São Paulo, Brazil
                [21 ]Hospital Universitário de Cascavel, Cascavel, Brazil
                [22 ]Hospital Sírio Libanês, São Paulo, Brazil
                [23 ]Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
                [24 ]School of Medicine, Federal University of Health Sciences, Porto Alegre, Brazil
                [25 ]for the BaSICS investigators and the BRICNet members
                Article
                10.1001/jama.2021.11684
                34375394
                472ddc88-c965-48f4-af2c-b733a4e3e377
                © 2021
                History

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