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      Nonlinear wave evolution with data-driven breaking

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          Abstract

          Wave breaking is the main mechanism that dissipates energy input into ocean waves by wind and transferred across the spectrum by nonlinearity. It determines the properties of a sea state and plays a crucial role in ocean-atmosphere interaction, ocean pollution, and rogue waves. Owing to its turbulent nature, wave breaking remains too computationally demanding to solve using direct numerical simulations except in simple, short-duration circumstances. To overcome this challenge, we present a blended machine learning framework in which a physics-based nonlinear evolution model for deep-water, non-breaking waves and a recurrent neural network are combined to predict the evolution of breaking waves. We use wave tank measurements rather than simulations to provide training data and use a long short-term memory neural network to apply a finite-domain correction to the evolution model. Our blended machine learning framework gives excellent predictions of breaking and its effects on wave evolution, including for external data.

          Abstract

          Wave breaking mechanisms relevant for modelling of ocean-atmosphere interaction and rogue waves, remain computationally challenging. The authors propose a machine learning framework for prediction of breaking and its effects on wave evolution that can be applied for forecasting of real world sea states.

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          Long Short-Term Memory

          Learning to store information over extended time intervals by recurrent backpropagation takes a very long time, mostly because of insufficient, decaying error backflow. We briefly review Hochreiter's (1991) analysis of this problem, then address it by introducing a novel, efficient, gradient-based method called long short-term memory (LSTM). Truncating the gradient where this does not do harm, LSTM can learn to bridge minimal time lags in excess of 1000 discrete-time steps by enforcing constant error flow through constant error carousels within special units. Multiplicative gate units learn to open and close access to the constant error flow. LSTM is local in space and time; its computational complexity per time step and weight is O(1). Our experiments with artificial data involve local, distributed, real-valued, and noisy pattern representations. In comparisons with real-time recurrent learning, back propagation through time, recurrent cascade correlation, Elman nets, and neural sequence chunking, LSTM leads to many more successful runs, and learns much faster. LSTM also solves complex, artificial long-time-lag tasks that have never been solved by previous recurrent network algorithms.
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            Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study

            Our previous study demonstrated increased expression of Heat shock protein (Hsp) 90 in the skin of patients with systemic sclerosis (SSc). We aimed to evaluate plasma Hsp90 in SSc and characterize its association with SSc-related features. Ninety-two SSc patients and 92 age-/sex-matched healthy controls were recruited for the cross-sectional analysis. The longitudinal analysis comprised 30 patients with SSc associated interstitial lung disease (ILD) routinely treated with cyclophosphamide. Hsp90 was increased in SSc compared to healthy controls. Hsp90 correlated positively with C-reactive protein and negatively with pulmonary function tests: forced vital capacity and diffusing capacity for carbon monoxide (DLCO). In patients with diffuse cutaneous (dc) SSc, Hsp90 positively correlated with the modified Rodnan skin score. In SSc-ILD patients treated with cyclophosphamide, no differences in Hsp90 were found between baseline and after 1, 6, or 12 months of therapy. However, baseline Hsp90 predicts the 12-month change in DLCO. This study shows that Hsp90 plasma levels are increased in SSc patients compared to age-/sex-matched healthy controls. Elevated Hsp90 in SSc is associated with increased inflammatory activity, worse lung functions, and in dcSSc, with the extent of skin involvement. Baseline plasma Hsp90 predicts the 12-month change in DLCO in SSc-ILD patients treated with cyclophosphamide.
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              Physics-Informed Neural Networks: A Deep Learning Framework for Solving Forward and Inverse Problems Involving Nonlinear Partial Differential Equations

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                Author and article information

                Contributors
                eeltink@mit.edu
                sapsis@mit.edu
                Journal
                Nat Commun
                Nat Commun
                Nature Communications
                Nature Publishing Group UK (London )
                2041-1723
                29 April 2022
                29 April 2022
                2022
                : 13
                : 2343
                Affiliations
                [1 ]GRID grid.116068.8, ISNI 0000 0001 2341 2786, Department of Mechanical Engineering, , Massachusetts Institute of Technology, ; Cambridge, MA United States
                [2 ]GRID grid.4991.5, ISNI 0000 0004 1936 8948, Department of Engineering Science, , University of Oxford, ; Oxford, UK
                [3 ]GRID grid.462174.2, ISNI 0000 0000 9326 0047, Aix-Marseille University, CNRS, Centrale Marseille, IRPHE, ; Marseille, France
                [4 ]GRID grid.1013.3, ISNI 0000 0004 1936 834X, Centre for Wind, Waves and Water, School of Civil Engineering, , The University of Sydney, ; Sydney, NSW Australia
                [5 ]GRID grid.258799.8, ISNI 0000 0004 0372 2033, Disaster Prevention Research Institute, , Kyoto University, ; Kyoto, Japan
                [6 ]GRID grid.258799.8, ISNI 0000 0004 0372 2033, Hakubi Center for Advanced Research, , Kyoto University, ; Kyoto, Japan
                [7 ]GRID grid.8591.5, ISNI 0000 0001 2322 4988, Group of Applied Physics and Institute for Environmental Sciences, , University of Geneva, ; Geneva, Switzerland
                [8 ]GRID grid.5292.c, ISNI 0000 0001 2097 4740, Faculty of Civil Engineering and Geosciences, , Delft University of Technology, ; Delft, The Netherlands
                Author information
                http://orcid.org/0000-0003-4560-2956
                http://orcid.org/0000-0003-0430-6472
                http://orcid.org/0000-0002-5473-3029
                http://orcid.org/0000-0003-2398-3882
                Article
                30025
                10.1038/s41467-022-30025-z
                9054829
                35487899
                43c4f51b-e134-4088-aee1-c5963942309a
                © The Author(s) 2022

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 13 August 2021
                : 17 March 2022
                Funding
                Funded by: FundRef https://doi.org/10.13039/501100001711, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation);
                Award ID: P2GEP2-191480
                Award ID: 200020-175697
                Award Recipient :
                Categories
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                Custom metadata
                © The Author(s) 2022

                Uncategorized
                physical oceanography,fluid dynamics
                Uncategorized
                physical oceanography, fluid dynamics

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