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      Clustering Analysis of Aging Diseases and Chronic Habits With Multivariate Time Series Electrocardiogram and Medical Records

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          Abstract

          Background

          With recent technology, multivariate time-series electrocardiogram (ECG) analysis has played an important role in diagnosing cardiovascular diseases. However, discovering the association of wide range aging disease and chronic habit with ECG analysis still has room to be explored. This article mainly analyzes the possible relationship between common aging diseases or chorionic habits of medical record and ECG, such as diabetes, obesity, and hypertension, or the habit of smoking.

          Methods

          In the research, we first conducted different ECG features, such as those of reduced binary pattern, waveform, and wavelet and then performed a k-means clustering analysis on the correlation between ECGs and the aforementioned diseases and habits, from which it is expected to find a firm association between them and the best characteristics that can be used for future research.

          Results

          In summary, we discovered a weak and strong evidence between ECG and medical records. For strong evidence, most patients with diabetes are always assigned into a specified group no matter the number of classes in the k-means clustering, which means we can find their association between them. For weak evidence, smokers, obesity, and hypertension have less unique ECG feature vector, enabling clustering them into specific groups, so the ECGs might be used to identify smokers, obesity, and hypertension. It is also interesting that we found obesity and hypertension, which are thought to be related to cardiovascular system. However, they are not highly correlated in our clustering analysis, which might indirectly tell us that the impact of obesity and hypertension to our body is various. In addition, the clustering effect of waveform feature is better than the other two methods.

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          Most cited references25

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          ECG signal denoising and baseline wander correction based on the empirical mode decomposition.

          The electrocardiogram (ECG) is widely used for diagnosis of heart diseases. Good quality ECG are utilized by physicians for interpretation and identification of physiological and pathological phenomena. However, in real situations, ECG recordings are often corrupted by artifacts. Two dominant artifacts present in ECG recordings are: (1) high-frequency noise caused by electromyogram induced noise, power line interferences, or mechanical forces acting on the electrodes; (2) baseline wander (BW) that may be due to respiration or the motion of the patients or the instruments. These artifacts severely limit the utility of recorded ECGs and thus need to be removed for better clinical evaluation. Several methods have been developed for ECG enhancement. In this paper, we propose a new ECG enhancement method based on the recently developed empirical mode decomposition (EMD). The proposed EMD-based method is able to remove both high-frequency noise and BW with minimum signal distortion. The method is validated through experiments on the MIT-BIH databases. Both quantitative and qualitative results are given. The simulations show that the proposed EMD-based method provides very good results for denoising and BW removal.
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            ECG Signal Denoising By Wavelet Transform Thresholding

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              • Abstract: not found
              • Article: not found

              Nutzung der EKG-Signaldatenbank CARDIODAT der PTB über das Internet

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                Author and article information

                Contributors
                Journal
                Front Aging Neurosci
                Front Aging Neurosci
                Front. Aging Neurosci.
                Frontiers in Aging Neuroscience
                Frontiers Media S.A.
                1663-4365
                05 May 2020
                2020
                : 12
                : 95
                Affiliations
                [1] 1School of Computer Science and Technology, Harbin Institute of Technology (Shenzhen) , Shenzhen, China
                [2] 2Department of Family Medicine, Taichung Veterans General Hospital , Taichung, Taiwan
                [3] 3Center for Geriatrics and Gerontology, Taichung Veterans General Hospital , Taichung, Taiwan
                [4] 4Computer and Communication Center, Taichung Veterans General Hospital , Taichung, Taiwan
                Author notes

                Edited by: Jiehui Jiang, Shanghai University, China

                Reviewed by: Weijia Lu, Affiliated Hospital of Nantong University, China; Chin Chieh Wu, Chang Gung University, Taiwan

                *Correspondence: Kuo-Kun Tseng, kktseng@ 123456hit.edu.cn
                Article
                10.3389/fnagi.2020.00095
                7232580
                32477093
                439852d4-ed07-438b-9367-6f03f55d1d42
                Copyright © 2020 Tseng, Li, Tang, Yang, Lin and Zhao.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 30 October 2019
                : 20 March 2020
                Page count
                Figures: 6, Tables: 4, Equations: 3, References: 26, Pages: 10, Words: 0
                Categories
                Neuroscience
                Original Research

                Neurosciences
                electrocardiogram,disease analysis,habit analysis,feature extraction,k-means clustering

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