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      A multinational Delphi consensus to end the COVID-19 public health threat

      research-article
      1 , 2 , 3 , , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 1 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 3 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 3 , The COVID-19 Consensus Statement Panel
      Nature
      Nature Publishing Group UK
      Public health, Policy, Health policy

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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Despite notable scientific and medical advances, broader political, socioeconomic and behavioural factors continue to undercut the response to the COVID-19 pandemic 1, 2 . Here we convened, as part of this Delphi study, a diverse, multidisciplinary panel of 386 academic, health, non-governmental organization, government and other experts in COVID-19 response from 112 countries and territories to recommend specific actions to end this persistent global threat to public health. The panel developed a set of 41 consensus statements and 57 recommendations to governments, health systems, industry and other key stakeholders across six domains: communication; health systems; vaccination; prevention; treatment and care; and inequities. In the wake of nearly three years of fragmented global and national responses, it is instructive to note that three of the highest-ranked recommendations call for the adoption of whole-of-society and whole-of-government approaches 1 , while maintaining proven prevention measures using a vaccines-plus approach 2 that employs a range of public health and financial support measures to complement vaccination. Other recommendations with at least 99% combined agreement advise governments and other stakeholders to improve communication, rebuild public trust and engage communities 3 in the management of pandemic responses. The findings of the study, which have been further endorsed by 184 organizations globally, include points of unanimous agreement, as well as six recommendations with >5% disagreement, that provide health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.

          Abstract

          A diverse, multidisciplinary panel of 386 experts in COVID-19 response from 112 countries provides health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.

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          Most cited references126

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          • Abstract: found
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          Is Open Access

          Vaccine hesitancy: Definition, scope and determinants.

          The SAGE Working Group on Vaccine Hesitancy concluded that vaccine hesitancy refers to delay in acceptance or refusal of vaccination despite availability of vaccination services. Vaccine hesitancy is complex and context specific, varying across time, place and vaccines. It is influenced by factors such as complacency, convenience and confidence. The Working Group retained the term 'vaccine' rather than 'vaccination' hesitancy, although the latter more correctly implies the broader range of immunization concerns, as vaccine hesitancy is the more commonly used term. While high levels of hesitancy lead to low vaccine demand, low levels of hesitancy do not necessarily mean high vaccine demand. The Vaccine Hesitancy Determinants Matrix displays the factors influencing the behavioral decision to accept, delay or reject some or all vaccines under three categories: contextual, individual and group, and vaccine/vaccination-specific influences.
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            • Record: found
            • Abstract: found
            • Article: not found

            A global survey of potential acceptance of a COVID-19 vaccine

            Several coronavirus disease 2019 (COVID-19) vaccines are currently in human trials. In June 2020, we surveyed 13,426 people in 19 countries to determine potential acceptance rates and factors influencing acceptance of a COVID-19 vaccine. Of these, 71.5% of participants reported that they would be very or somewhat likely to take a COVID-19 vaccine, and 61.4% reported that they would accept their employer’s recommendation to do so. Differences in acceptance rates ranged from almost 90% (in China) to less than 55% (in Russia). Respondents reporting higher levels of trust in information from government sources were more likely to accept a vaccine and take their employer’s advice to do so.
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              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              More than 50 long-term effects of COVID-19: a systematic review and meta-analysis

              COVID-19 can involve persistence, sequelae, and other medical complications that last weeks to months after initial recovery. This systematic review and meta-analysis aims to identify studies assessing the long-term effects of COVID-19. LitCOVID and Embase were searched to identify articles with original data published before the 1st of January 2021, with a minimum of 100 patients. For effects reported in two or more studies, meta-analyses using a random-effects model were performed using the MetaXL software to estimate the pooled prevalence with 95% CI. PRISMA guidelines were followed. A total of 18,251 publications were identified, of which 15 met the inclusion criteria. The prevalence of 55 long-term effects was estimated, 21 meta-analyses were performed, and 47,910 patients were included (age 17–87 years). The included studies defined long-COVID as ranging from 14 to 110 days post-viral infection. It was estimated that 80% of the infected patients with SARS-CoV-2 developed one or more long-term symptoms. The five most common symptoms were fatigue (58%), headache (44%), attention disorder (27%), hair loss (25%), and dyspnea (24%). Multi-disciplinary teams are crucial to developing preventive measures, rehabilitation techniques, and clinical management strategies with whole-patient perspectives designed to address long COVID-19 care.
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                Author and article information

                Contributors
                Jeffrey.Lazarus@isglobal.org
                Journal
                Nature
                Nature
                Nature
                Nature Publishing Group UK (London )
                0028-0836
                1476-4687
                3 November 2022
                3 November 2022
                2022
                : 611
                : 7935
                : 332-345
                Affiliations
                [1 ]GRID grid.434607.2, ISNI 0000 0004 1763 3517, Barcelona Institute for Global Health (ISGlobal), ; Barcelona, Spain
                [2 ]GRID grid.5841.8, ISNI 0000 0004 1937 0247, Faculty of Medicine and Health Sciences, , University of Barcelona, ; Barcelona, Spain
                [3 ]GRID grid.212340.6, ISNI 0000000122985718, City University of New York Graduate School of Public Health and Health Policy (CUNY SPH), ; New York City, NY USA
                [4 ]Independent Researcher, Sioux Falls, SD USA
                [5 ]GRID grid.16463.36, ISNI 0000 0001 0723 4123, University of KwaZulu-Natal, ; Durban, South Africa
                [6 ]GRID grid.428428.0, ISNI 0000 0004 5938 4248, Centre for the AIDS Program of Research in South Africa (CAPRISA), ; Durban, South Africa
                [7 ]GRID grid.5386.8, ISNI 000000041936877X, Weill Cornell Medicine, Cornell University, ; Ithaca, NY USA
                [8 ]GRID grid.416973.e, ISNI 0000 0004 0582 4340, Weill Cornell Medicine-Qatar, Cornell University, Qatar Foundation-Education City, ; Doha, Qatar
                [9 ]Pan American Health Organisation, Washington, DC USA
                [10 ]UNITE Global Parliamentarians Network, Lisbon, Portugal
                [11 ]GRID grid.5012.6, ISNI 0000 0001 0481 6099, Faculty of Health, Medicine and Life Sciences, Maastricht University, ; Maastricht, The Netherlands
                [12 ]GRID grid.7831.d, ISNI 000000010410653X, Institute of Health Sciences (CIIS), Catholic University of Portugal, ; Lisbon, Portugal
                [13 ]GRID grid.430503.1, ISNI 0000 0001 0703 675X, University of Colorado School of Medicine, ; Aurora, CO USA
                [14 ]GRID grid.418068.3, ISNI 0000 0001 0723 0931, Oswaldo Cruz Foundation (Fiocruz), ; Rio de Janeiro, Brazil
                [15 ]GRID grid.8399.b, ISNI 0000 0004 0372 8259, University of Bahia, ; Salvador, Brazil
                [16 ]GRID grid.419985.8, ISNI 0000 0001 1016 8825, New England Complex Systems Institute, ; Cambridge, MA USA
                [17 ]GRID grid.452366.0, ISNI 0000 0000 9638 9567, Manhiça Health Research Center (CISM), ; Maputo, Mozambique
                [18 ]GRID grid.425902.8, ISNI 0000 0000 9601 989X, Catalan Institute for Research and Advanced Studies (ICREA), ; Barcelona, Spain
                [19 ]GRID grid.5841.8, ISNI 0000 0004 1937 0247, Pediatrics Department, Hospital Sant Joan de Déu, , University of Barcelona, ; Barcelona, Spain
                [20 ]GRID grid.466571.7, ISNI 0000 0004 1756 6246, Biomedical Research Consortium in Epidemiology and Public Health (CIBERESP), ; Madrid, Spain
                [21 ]GRID grid.452586.8, ISNI 0000 0001 1012 9674, Doctors Without Borders (MSF), ; Geneva, Switzerland
                [22 ]Baraka Impact Finance, Geneva, Switzerland
                [23 ]GRID grid.254549.b, ISNI 0000 0004 1936 8155, Payne Institute, Colorado School of Mines, ; Golden, CO USA
                [24 ]GRID grid.260539.b, ISNI 0000 0001 2059 7017, National Yang Ming Chiao Tung University, ; Taipei, Taiwan
                [25 ]GRID grid.189967.8, ISNI 0000 0001 0941 6502, Emory School of Medicine, ; Atlanta, GA USA
                [26 ]GRID grid.1005.4, ISNI 0000 0004 4902 0432, University of New South Wales (UNSW) Sydney, ; Sydney, New South Wales Australia
                [27 ]GRID grid.198530.6, ISNI 0000 0000 8803 2373, Chinese Center for Disease Control and Prevention, ; Beijing, China
                [28 ]GRID grid.213910.8, ISNI 0000 0001 1955 1644, The O’Neill Institute for National and Global Health Law, Georgetown University, ; Washington, DC USA
                [29 ]GRID grid.1056.2, ISNI 0000 0001 2224 8486, Burnet Institute, ; Melbourne, Victoria Australia
                [30 ]GRID grid.266190.a, ISNI 0000000096214564, Department of Chemistry, , University of Colorado Boulder, ; Boulder, CO USA
                [31 ]GRID grid.266190.a, ISNI 0000000096214564, Cooperative Institute for Research in Environmental Sciences (CIRES), , University of Colorado Boulder, ; Boulder, CO USA
                [32 ]GRID grid.11586.3b, ISNI 0000 0004 1767 8969, Christian Medical College (CMC), ; Vellore, India
                [33 ]GRID grid.479627.9, ISNI 0000 0004 7677 5267, Wilton Park, ; Steyning, UK
                [34 ]GRID grid.29524.38, ISNI 0000 0004 0571 7705, Clinic for Infectious Diseases and Febrile Illnesses, , University Medical Centre, ; Ljubljana, Slovenia
                [35 ]GRID grid.8954.0, ISNI 0000 0001 0721 6013, Faculty of Medicine, , University of Ljubljana, ; Ljubljana, Slovenia
                [36 ]GRID grid.8991.9, ISNI 0000 0004 0425 469X, The London School of Hygiene & Tropical Medicine, ; London, UK
                [37 ]GRID grid.502951.a, ISNI 0000 0004 0563 8935, University Teaching Hospital of Butare, ; Butare, Rwanda
                [38 ]GRID grid.11024.36, ISNI 0000000120977052, Paris Dauphine University - PSL, ; Paris, France
                [39 ]GRID grid.4444.0, ISNI 0000 0001 2112 9282, French National Centre for Scientific Research (CNRS), ; Grenoble, France
                [40 ]GRID grid.83440.3b, ISNI 0000000121901201, University College London (UCL), ; London, UK
                [41 ]GRID grid.459475.e, ISNI 0000 0004 1800 6232, Dr. Rajendra Prasad Government Medical College, ; Himachal Pradesh, India
                [42 ]GRID grid.52681.38, ISNI 0000 0001 0746 8691, James P. Grant School of Public Health, , BRAC University, ; Dhaka, Bangladesh
                [43 ]Plenitud Foundation, Santo Domingo, Dominican Republic
                [44 ]GRID grid.412889.e, ISNI 0000 0004 1937 0706, University of Costa Rica, ; San José, Costa Rica
                [45 ]GRID grid.9654.e, ISNI 0000 0004 0372 3343, Faculty of Medical and Health Sciences, , University of Auckland, ; Auckland, New Zealand
                [46 ]Independent Philosopher, Copenhagen, Denmark
                [47 ]GRID grid.63368.38, ISNI 0000 0004 0445 0041, Department of Neurosurgery, Houston Methodist Research Institute, ; Houston, TX USA
                [48 ]International Digital Health & AI Research Collaborative (I-DAIR), Geneva, Switzerland
                [49 ]GRID grid.507436.3, ISNI 0000 0004 8340 5635, University of Global Health Equity, ; Kigali, Rwanda
                [50 ]GRID grid.10347.31, ISNI 0000 0001 2308 5949, University of Malaya, ; Kuala Lumpur, Malaysia
                [51 ]GRID grid.414543.3, ISNI 0000 0000 9144 642X, Ifakara Health Institute, ; Dar es Salaam, Tanzania
                [52 ]GRID grid.28046.38, ISNI 0000 0001 2182 2255, University of Ottawa, ; Ottawa, Ontario Canada
                [53 ]Baku Health Centre, Baku, Azerbaijan
                [54 ]GRID grid.5379.8, ISNI 0000000121662407, The University of Manchester, ; Manchester, UK
                [55 ]GRID grid.429742.e, Mogadishu University, ; Mogadishu, Somalia
                [56 ]Generations for Health, Madrid, Spain
                [57 ]GRID grid.24381.3c, ISNI 0000 0000 9241 5705, Karolinska University Hospital, ; Stockholm, Sweden
                [58 ]Ministry of Health and Population, Port-au-Prince, Haiti
                [59 ]GRID grid.79730.3a, ISNI 0000 0001 0495 4256, Moi University, ; Eldoret, Kenya
                [60 ]Hurlingham National University, Hurlingham, Argentina
                [61 ]GRID grid.424404.2, ISNI 0000 0001 2296 9873, Graduate Institute of International and Development Studies, ; Geneva, Switzerland
                [62 ]GRID grid.415310.2, ISNI 0000 0001 2191 4301, King Faisal Specialist Hospital and Research Centre, ; Riyadh, Saudi Arabia
                [63 ]GRID grid.416646.7, ISNI 0000 0004 0621 3322, Salmaniya Medical Complex, ; Manama, Bahrain
                [64 ]GRID grid.9829.a, ISNI 0000000109466120, Kwame Nkrumah University of Science and Technology, ; Kumasi, Ghana
                [65 ]GRID grid.449178.7, ISNI 0000 0004 5894 7096, Trivedi School of Biosciences, Ashoka University, ; Sonepat, India
                [66 ]GRID grid.7269.a, ISNI 0000 0004 0621 1570, Community Medicine Department, Faculty of Medicine, , Ain Shams University, ; Cairo, Egypt
                [67 ]GRID grid.441811.9, ISNI 0000 0004 0487 6309, Faculty of Health and Social Sciences, University of The Americas, ; Santiago, Chile
                [68 ]GRID grid.17089.37, ISNI 0000 0001 2190 316X, University of Alberta, ; Edmonton, Alberta Canada
                [69 ]GRID grid.449729.5, ISNI 0000 0004 7707 5975, University of Health and Allied Sciences, ; Ho, Volta Ghana
                [70 ]GRID grid.29980.3a, ISNI 0000 0004 1936 7830, University of Otago, ; Wellington, New Zealand
                [71 ]GRID grid.11899.38, ISNI 0000 0004 1937 0722, University of Sao Paulo, ; Sao Paulo, Brazil
                [72 ]European Public Health Alliance, Brussels, Belgium
                [73 ]Ministry of Health and Wellness Belize, Belmopan, Belize
                [74 ]Aids Healthcare Foundation, São Paulo, Brazil
                [75 ]GRID grid.10548.38, ISNI 0000 0004 1936 9377, Department of Physics, , Stockholm University, ; Stockholm, Sweden
                [76 ]GRID grid.189504.1, ISNI 0000 0004 1936 7558, Boston University Center for Emerging Infectious Diseases Policy and Research (CEID), ; Boston, MA USA
                [77 ]GRID grid.413027.3, ISNI 0000 0004 1767 7704, Centre For Ethics, , Yenepoya University, ; Mangaluru, India
                [78 ]Smart Phases, Plattsburgh, NY USA
                [79 ]Bitran y Asociados, Santiago, Chile
                [80 ]GRID grid.5292.c, ISNI 0000 0001 2097 4740, Delft University of Technology, ; Delft, The Netherlands
                [81 ]Transmissible, Houten, The Netherlands
                [82 ]GRID grid.6738.a, ISNI 0000 0001 1090 0254, Institute of Genetics, , Technische Universität Braunschweig, ; Braunschweig, Germany
                [83 ]GRID grid.436296.c, ISNI 0000 0001 2203 2044, Management Sciences for Health, ; Medford, MA USA
                [84 ]GRID grid.11951.3d, ISNI 0000 0004 1937 1135, University of the Witwatersrand, ; Johannesburg, South Africa
                [85 ]GRID grid.33058.3d, ISNI 0000 0001 0155 5938, Kenya Medical Research Institute, ; Nairobi, Kenya
                [86 ]GRID grid.21003.30, ISNI 0000 0004 1762 1962, University of Cassino and Southern Lazio, ; Cassino, Italy
                [87 ]GRID grid.13097.3c, ISNI 0000 0001 2322 6764, King’s College London, ; London, UK
                [88 ]GRID grid.11194.3c, ISNI 0000 0004 0620 0548, Department of Medicine, , Makerere University College of Health Sciences, ; Kampala, Uganda
                [89 ]GRID grid.412187.9, ISNI 0000 0000 9631 4901, Universidad del Desarrollo, ; Santiago, Chile
                [90 ]GRID grid.452482.d, ISNI 0000 0001 1551 6921, The Global Fund, ; Geneva, Switzerland
                [91 ]GRID grid.8142.f, ISNI 0000 0001 0941 3192, Catholic University of the Sacred Heart, ; Rome, Italy
                [92 ]GRID grid.12984.36, ISNI 0000 0000 8914 5257, University of Zambia, ; Lusaka, Zambia
                [93 ]Fattouma Bourguiba Teaching Hospital, Monastir, Tunisia
                [94 ]GRID grid.6572.6, ISNI 0000 0004 1936 7486, Institute of Applied Health Research, , University of Birmingham, ; Birmingham, UK
                [95 ]GRID grid.450284.f, Ministry of Health Seychelles, ; Victoria, Seychelles
                [96 ]GRID grid.410591.8, ISNI 0000 0000 8990 1788, National Aerospace University “Kharkiv Aviation Institute”, ; Kharkiv, Ukraine
                [97 ]GRID grid.47100.32, ISNI 0000000419368710, Yale School of Public Health, ; New Haven, CT USA
                [98 ]GRID grid.5335.0, ISNI 0000000121885934, University of Cambridge, ; Cambridge, UK
                [99 ]GRID grid.476980.4, Cairo University Hospitals, ; Cairo, Egypt
                [100 ]Africa Research Excellence Fund (AREF), London, UK
                [101 ]GRID grid.416850.e, ISNI 0000 0001 0698 4037, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, ; Mexico City, Mexico
                [102 ]Onom Foundation, Ulaanbaatar, Mongolia
                [103 ]GRID grid.7489.2, ISNI 0000 0004 1937 0511, Ben Gurion University of the Negev, ; Be’er Sheva, Israel
                [104 ]GRID grid.454780.a, ISNI 0000 0001 0683 2228, National Centre for Disease Control and National Vector Borne Disease Control Programme, Government of India, ; Delhi, India
                [105 ]GRID grid.5100.4, ISNI 0000 0001 2322 497X, University of Bucharest, ; Bucharest, Romania
                [106 ]GRID grid.15876.3d, ISNI 0000000106887552, Koç University İşbank Center for Infectious Diseases, ; Istanbul, Turkey
                [107 ]GRID grid.442859.6, ISNI 0000 0004 0410 1351, Kabul University of Medical Sciences, ; Kabul, Afghanistan
                [108 ]GRID grid.8761.8, ISNI 0000 0000 9919 9582, University of Gothenburg, ; Gothenburg, Sweden
                [109 ]GRID grid.441637.3, ISNI 0000 0001 0690 3540, CONICET/National University of Tres de Febrero, ; Caseros, Argentina
                [110 ]GRID grid.433854.d, ISNI 0000 0001 0266 1628, Federation of American Scientists, ; Washington, DC USA
                [111 ]Social Security Board, Belize City, Belize
                [112 ]GRID grid.461576.7, ISNI 0000 0000 8786 7651, The University of the West Indies, ; Kingston, Jamaica
                [113 ]GRID grid.4280.e, ISNI 0000 0001 2180 6431, National University of Singapore, ; Singapore, Singapore
                [114 ]GRID grid.507190.a, Center for the Study of Equity and Governance in Health Systems, ; Guatemala City, Guatemala
                [115 ]Biomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela
                [116 ]GRID grid.34477.33, ISNI 0000000122986657, Department of Health Metrics Sciences, University of Washington, ; Seattle, WA USA
                [117 ]GRID grid.429654.8, ISNI 0000 0004 5345 9480, National Center for Disease Control and Public Health of Georgia, ; Tbilisi, Georgia
                [118 ]GRID grid.266102.1, ISNI 0000 0001 2297 6811, UCSF, ; San Francisco, CA USA
                [119 ]GRID grid.11100.31, ISNI 0000 0001 0673 9488, School of Public Health, , Cayetano Heredia University, ; Lima, Peru
                [120 ]GRID grid.59734.3c, ISNI 0000 0001 0670 2351, Icahn School of Medicine at Mount Sinai, ; New York City, NY USA
                [121 ]GRID grid.414698.6, ISNI 0000 0004 1767 743X, MAMC & Associated Hospitals New Delhi, ; New Delhi, India
                [122 ]GRID grid.12364.32, ISNI 0000 0004 0647 9497, University of Lomé, ; Lomé, Togo
                [123 ]GRID grid.9486.3, ISNI 0000 0001 2159 0001, Universidad Nacional Autonoma de Mexico, ; Mexico City, Mexico
                [124 ]Organised Medicine Academic Guild—OMAG, Mumbai, India
                [125 ]GRID grid.412358.9, ISNI 0000 0001 1954 8293, Simon Bolivar University, ; Caracas, Venezuela
                [126 ]GRID grid.18098.38, ISNI 0000 0004 1937 0562, University of Haifa, ; Haifa, Israel
                [127 ]GRID grid.4991.5, ISNI 0000 0004 1936 8948, University of Oxford, ; Oxford, UK
                [128 ]GRID grid.1003.2, ISNI 0000 0000 9320 7537, University of Queensland, ; Brisbane, Queensland Australia
                [129 ]GRID grid.9909.9, ISNI 0000 0004 1936 8403, University of Leeds, ; Leeds, UK
                [130 ]National Institute of Infectology Evandro Chagas-Fiocruz, Rio de Janeiro, Brazil
                [131 ]GRID grid.19096.37, ISNI 0000 0004 1767 225X, Indian Council of Medical Research, ; New Delhi, India
                [132 ]GRID grid.415771.1, ISNI 0000 0004 1773 4764, National Institute of Public Health, ; Cuernavaca, Mexico
                [133 ]GRID grid.416846.9, ISNI 0000 0004 0571 4942, St Luke’s Medical Center College of Medicine, ; Quezon City, The Philippines
                [134 ]GRID grid.13339.3b, ISNI 0000000113287408, Department of Public Health, , Medical University of Warsaw, ; Warsaw, Poland
                [135 ]GRID grid.512925.8, ISNI 0000 0004 7592 6297, Ankara City Hospital Infectious Diseases and Clinical Mirobiology, ; Ankara, Turkey
                [136 ]Independent Researcher, Port Louis, Mauritius
                [137 ]GRID grid.466905.8, Ministry of Health, ; Colombo, Sri Lanka
                [138 ]Ateneo School of Government, Quezon City, The Philippines
                [139 ]Independent Consultant, Cairo, Egypt
                [140 ]GRID grid.7737.4, ISNI 0000 0004 0410 2071, University of Helsinki, ; Helsinki, Finland
                [141 ]GRID grid.265892.2, ISNI 0000000106344187, University of Alabama at Birmingham, ; Birmingham, AL USA
                [142 ]GRID grid.39382.33, ISNI 0000 0001 2160 926X, National School of Tropical Medicine, Baylor College of Medicine, ; Houston, TX USA
                [143 ]19 To Zero, Calgary, Alberta Canada
                [144 ]GRID grid.472484.9, ISNI 0000 0001 2188 6187, Center for Disease Control and Geohealth Studies, , Academy of Sciences and Arts of Bosnia and Herzegovina, ; Sarajevo, Bosnia and Herzegovina
                [145 ]GRID grid.494032.8, ISNI 0000 0000 9193 7763, COHRED, ; Geneva, Switzerland
                [146 ]Independent Consultant, Cairo, Egypt
                [147 ]GRID grid.419324.9, ISNI 0000 0004 0508 0388, International Center for Research on Women, ; Washington, DC USA
                [148 ]Centre for Digital Therapeutics, Toronto, Ontario Canada
                [149 ]GRID grid.7147.5, ISNI 0000 0001 0633 6224, Aga Khan University, ; Karachi, Pakistan
                [150 ]GRID grid.137628.9, ISNI 0000 0004 1936 8753, NYU Grossman School of Medicine, ; New York City, NY USA
                [151 ]GRID grid.31143.34, ISNI 0000 0001 2168 4024, School of Medicine and Pharmacy, , University Mohammed V, ; Rabat, Morocco
                [152 ]GRID grid.17063.33, ISNI 0000 0001 2157 2938, University of Toronto, ; Toronto, Ontario Canada
                [153 ]GRID grid.449798.f, ISNI 0000 0004 0506 1080, Research Centre of Public Health, Faculty of Health, , University of Vlore “Ismail Qemali” Albania, ; Vlorë, Albania
                [154 ]GRID grid.415738.c, ISNI 0000 0000 9216 2496, Gamaleya National Research Center for Epidemiology and Microbiology of the Ministry of Health of the Russian Federation, ; Moscow, Russian Federation
                [155 ]GRID grid.168010.e, ISNI 0000000419368956, Division of Infectious Disease & Geographic Medicine, , Stanford University, ; Stanford, CA USA
                [156 ]Kamuzu University of Health Sciences, Blantyre, Malawi
                [157 ]GRID grid.416132.3, ISNI 0000 0004 1772 5665, Royal Hospital, Ministry of Health, ; Muscat, Oman
                [158 ]GRID grid.430880.7, ISNI 0000 0004 0403 2931, Tashkent Pediatric Medical Institute, ; Tashkent, Uzbekistan
                [159 ]GRID grid.9918.9, ISNI 0000 0004 1936 8411, University of Leicester, ; Leicester, UK
                [160 ]African Center for Global Health and Social Transformation, Kampala, Uganda
                [161 ]GRID grid.222754.4, ISNI 0000 0001 0840 2678, Division of Infectious Diseases, Guro Hospital, , College of Medicine Korea University, ; Seoul, Republic of Korea
                [162 ]GRID grid.7634.6, ISNI 0000000109409708, Comenius University in Bratislava, ; Bratislava, Slovakia
                [163 ]GRID grid.264484.8, ISNI 0000 0001 2189 1568, Syracuse University, ; Syracuse, NY USA
                [164 ]GRID grid.26790.3a, ISNI 0000 0004 1936 8606, University of Miami Institute for Advanced Study of the Americas, ; Coral Gables, FL USA
                [165 ]GRID grid.507196.c, ISNI 0000 0004 9225 0356, Coalition of Epidemic Preparedness Innovations (CEPI), ; Oslo, Norway
                [166 ]Institute of Family Medicine and Primary Care, Greater Noida, India
                [167 ]GRID grid.13063.37, ISNI 0000 0001 0789 5319, London School of Economics & Political Science, ; London, UK
                [168 ]GRID grid.418449.4, ISNI 0000 0004 0379 5398, Bradford Institute for Health Research & Bradford Teaching Hospitals NHS Foundation Trust, ; Bradford, UK
                [169 ]GRID grid.264200.2, ISNI 0000 0000 8546 682X, St Georges University of London, ; London, UK
                [170 ]GRID grid.194645.b, ISNI 0000000121742757, The University of Hong Kong, ; Hong Kong, China
                [171 ]University Ziane Achour Djelfa, Djelfa, Algeria
                [172 ]GRID grid.7345.5, ISNI 0000 0001 0056 1981, University of Buenos Aires/Health Systems Global, ; Buenos Aires, Argentina
                [173 ]Faculty of Social and Human Sciences, Khemis-Miliana University, Khemis Miliana, Algeria
                [174 ]GRID grid.5216.0, ISNI 0000 0001 2155 0800, National and Kapodistrian University of Athens, ; Athens, Greece
                [175 ]GRID grid.411705.6, ISNI 0000 0001 0166 0922, Digestive Disease Research Institute Tehran University of Medical Sciences, ; Tehran, Iran
                [176 ]GRID grid.4991.5, ISNI 0000 0004 1936 8948, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, ; Oxford, UK
                [177 ]GRID grid.266813.8, ISNI 0000 0001 0666 4105, University of Nebraska Medical Center, ; Omaha, NE USA
                [178 ]GRID grid.438526.e, ISNI 0000 0001 0694 4940, Virginia Tech, ; Blacksburg, VA USA
                [179 ]University of Cabo Verde, Praia, Cape Verde
                [180 ]GRID grid.5338.d, ISNI 0000 0001 2173 938X, Department of Preventive Medicine and Public Health and INCLIVA, , University of Valencia, ; Valencia, Spain
                [181 ]Instituto #SaludsinBulos, Madrid, Spain
                [182 ]University of Health Sciences, Ministry of Health, Vientiane, Lao People’s Democratic Republic
                [183 ]GRID grid.452485.a, ISNI 0000 0001 1507 3147, Foundation for Innovative New Diagnostics, ; Geneva, Switzerland
                [184 ]GRID grid.503074.5, Institute of Health Research Epidemiological Surveillance and Trainings (IRESSEF), ; Dakar, Senegal
                [185 ]Universal Health Monitor, Bethesda, MD USA
                [186 ]GRID grid.8756.c, ISNI 0000 0001 2193 314X, University of Glasgow, ; Glasgow, UK
                [187 ]GRID grid.415998.8, ISNI 0000 0004 0445 6726, King Saud Medical City, Ministry of Health and College of Medicine Alfaisal University, ; Riyadh, Saudi Arabia
                [188 ]GRID grid.427788.6, ISNI 0000 0004 1766 1016, Amrita Institute of Medical Sciences, ; Kochi, India
                [189 ]GRID grid.419346.d, ISNI 0000 0004 0480 4882, International Food Policy Research Institute, ; New Delhi, India
                [190 ]Goldman Hine LLP, Toronto, Ontario Canada
                [191 ]GRID grid.412688.1, ISNI 0000 0004 0397 9648, Department of Gastroeterology, , University Hospital Center Riejka, ; Riejka, Croatia
                [192 ]GRID grid.7149.b, ISNI 0000 0001 2166 9385, School of Medicine, , University of Belgrade, ; Belgrade, Serbia
                [193 ]MaREI Centre, Ryan Institute & School of Engineering, University of Galway, Galway, Ireland
                [194 ]GRID grid.25152.31, ISNI 0000 0001 2154 235X, University of Saskatchewan, ; Saskatoon, Saskatchewan Canada
                [195 ]GRID grid.1003.2, ISNI 0000 0000 9320 7537, Queensland University of Technolgy, ; Brisbane, Queensland Australia
                [196 ]GRID grid.42629.3b, ISNI 0000000121965555, Department of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, ; Newcastle, UK
                [197 ]GRID grid.7155.6, ISNI 0000 0001 2260 6941, Faculty of Medicine, , Alexandria University, ; Alexandria, Egypt
                [198 ]GRID grid.238491.5, ISNI 0000 0004 0367 6866, New York State Department of Health, ; Albany, NY USA
                [199 ]GRID grid.22903.3a, ISNI 0000 0004 1936 9801, American University of Beirut, ; Beirut, Lebanon
                [200 ]Faith to Action Network, Nairobi, Kenya
                [201 ]GRID grid.410675.1, ISNI 0000 0001 2325 3084, International University of Catalonia, ; Barcelona, Spain
                [202 ]IntraHealth International, Nairobi, Kenya
                [203 ]GRID grid.413355.5, ISNI 0000 0001 2221 4219, African Population and Health Research Center, ; Nairobi, Kenya
                [204 ]GRID grid.508167.d, Africa Centers for Disease Control and Prevention (Africa CDC), ; Addis Ababa, Ethiopia
                [205 ]GRID grid.10267.32, ISNI 0000 0001 2194 0956, Masaryk University, ; Brno, Czech Republic
                [206 ]GRID grid.418751.e, ISNI 0000 0004 0385 8977, Institute of Hydromechanics, , National Academy of Sciences of Ukraine, ; Kiev, Ukraine
                [207 ]GRID grid.47100.32, ISNI 0000000419368710, Yale School of Medicine, ; New Haven, CT USA
                [208 ]GRID grid.419369.0, ISNI 0000 0000 9378 4481, International Livestock Research Institute, ; Nairobi, Kenya
                [209 ]GRID grid.7858.2, ISNI 0000 0001 0708 5391, University Clinic of Gastroenterohepatology, Faculty of Medicine, , University “Ss. Cyril and Methodius”, ; Skopje, Republic of Macedonia
                [210 ]GRID grid.7914.b, ISNI 0000 0004 1936 7443, University of Bergen, ; Bergen, Norway
                [211 ]GRID grid.449023.8, ISNI 0000 0004 1771 7446, College of Dentistry, , Dar Al Uloom University, ; Riyadh, Saudi Arabia
                [212 ]Congolese Foundation for Medical Research, Brazzaville, Republic of the Congo
                [213 ]GRID grid.10392.39, ISNI 0000 0001 2190 1447, Institute of Tropical Medicine, , University of Tübingen, ; Tübingen, Germany
                [214 ]Covid Action Group, World Health Network, Son, Norway
                [215 ]GRID grid.16477.33, ISNI 0000 0001 0668 8422, Department of Infectious Diseases, Internal Medicine, School of Medicine, , Marmara University, ; Istanbul, Turkey
                [216 ]Effective Basic Services (eBASE) Africa, Bamenda, Cameroon
                [217 ]GRID grid.8591.5, ISNI 0000 0001 2322 4988, University of Geneva, Institute of Global Health, ; Geneva, Switzerland
                [218 ]GRID grid.461048.f, ISNI 0000 0004 0459 9858, Franciscus Gasthuis en Vlietland, ; Rotterdam, The Netherlands
                [219 ]GRID grid.254444.7, ISNI 0000 0001 1456 7807, Wayne State University School of Medicine, ; Detroit, MI USA
                [220 ]International Independent Expert on Health Systems, Managua, Nicaragua
                [221 ]GRID grid.69566.3a, ISNI 0000 0001 2248 6943, Tohoku University Graduate School of Medicine, ; Sendai, Japan
                [222 ]McGill School of Population and Global Health, Montreal, Quebec Canada
                [223 ]Training for Health Equity Network: THEnet, New York City, NY USA
                [224 ]GRID grid.55602.34, ISNI 0000 0004 1936 8200, Dalhousie University, ; Halifax, Nova Scotia Canada
                [225 ]GRID grid.428391.5, ISNI 0000 0004 0618 1092, Drugs for Neglected Diseases initiative, ; Geneva, Switzerland
                [226 ]GRID grid.5252.0, ISNI 0000 0004 1936 973X, ifo Institute at the University of Munich, ; Munich, Germany
                [227 ]Two Oceans in Health, Santo Domingo, Dominican Republic
                [228 ]GRID grid.448980.9, ISNI 0000 0004 0444 7651, Vietnam One Health University Network (VOHUN), Hanoi University of Public Health (HUPH), ; Hanoi, Vietnam
                [229 ]Molinari Economic Institute, Paris, France
                [230 ]GRID grid.7345.5, ISNI 0000 0001 0056 1981, CIMA, UMI-IFAECI/CNRS, FCEyN, Universidad de Buenos Aires-UBA/CONICET, ; Buenos Aires, Argentina
                [231 ]National Health Care for the Homeless Council, Nashville, TN USA
                [232 ]GRID grid.439369.2, ISNI 0000 0004 0392 0021, Chelsea and Westminster Hospital, ; London, UK
                [233 ]GRID grid.10692.3c, ISNI 0000 0001 0115 2557, INFIQC-CONICET, National University of Córdoba, ; Córdoba, Argentina
                [234 ]Department of Botany, University of Chakwal, Chakwal, Pakistan
                [235 ]GRID grid.40263.33, ISNI 0000 0004 1936 9094, Brown University, ; Providence, RI USA
                [236 ]Institute for Global Health and Development, Bissau, Guinea-Bissau
                [237 ]GRID grid.413301.4, ISNI 0000 0001 0523 9342, NHS Greater Glasgow and Clyde, ; Glasgow, UK
                [238 ]GRID grid.5645.2, ISNI 000000040459992X, Erasmus University Medical Center, ; Rotterdam, The Netherlands
                [239 ]Africa Europe Foundation, Brussels, Belgium
                [240 ]GRID grid.418193.6, ISNI 0000 0001 1541 4204, Norwegian Institute of Public Health, ; Oslo, Norway
                [241 ]Kohelet Policy Forum, Jerusalem, Israel
                [242 ]GRID grid.7922.e, ISNI 0000 0001 0244 7875, Chulalongkorn University, ; Bangkok, Thailand
                [243 ]Research Institute of Virology under the Ministry of Health of Uzbekistan, Tashkent, Uzbekistan
                [244 ]GRID grid.466620.0, ISNI 0000 0004 9157 3284, Child Health Research Foundation, ; Dhaka, Bangladesh
                [245 ]GRID grid.415771.1, ISNI 0000 0004 1773 4764, National Institute of Public Health, ; Mexico City, Mexico
                [246 ]GRID grid.417645.5, ISNI 0000 0004 0444 3191, Center of Molecular Immunology, ; La Havana, Cuba
                [247 ]GRID grid.164295.d, ISNI 0000 0001 0941 7177, University of Maryland, ; College Park, MD USA
                [248 ]GRID grid.413548.f, ISNI 0000 0004 0571 546X, Internal Medicine Department, , Hamad Medical Corporation, ; Doha, Qatar
                [249 ]GRID grid.5675.1, ISNI 0000 0001 0416 9637, Technical University of Dortmund, ; Dortmund, Germany
                [250 ]GRID grid.266100.3, ISNI 0000 0001 2107 4242, University of California San Diego, ; San Diego, CA USA
                [251 ]GRID grid.414874.a, ISNI 0000 0004 0642 7021, Infectious Disease Department, , Izmir Katip Celebi University Ataturk Training and Research Hospital, ; Izmir, Turkey
                [252 ]GRID grid.449576.d, ISNI 0000 0004 5895 8692, Faculty of Medicine, , Syrian Private University, ; Damascus, Syrian Arab Republic
                [253 ]Department of Psychiatry, Jawahar Lal Nehru Memorial Hospital, Srinagar, India
                [254 ]GRID grid.418015.9, ISNI 0000 0004 0463 1467, Centre for Infectious Disease Research in Zambia (CIDRZ), ; Lusaka, Zambia
                [255 ]The Office of the Government of the Republic of Lithuania, Vilnius, Lithuania
                [256 ]CORE Group Polio Project India, Delhi, India
                [257 ]Independent Consultant, Quito, Ecuador
                [258 ]GRID grid.419303.c, ISNI 0000 0001 2180 9405, Institute of Experimental Psychology, Centre of Social and Psychological Sciences, , Slovak Academy of Sciences, ; Bratislava, Slovakia
                [259 ]GRID grid.15596.3e, ISNI 0000000102380260, Dublin City University, ; Dublin, Ireland
                [260 ]GRID grid.22072.35, ISNI 0000 0004 1936 7697, University of Calgary, ; Calgary, Alberta Canada
                [261 ]GRID grid.411729.8, ISNI 0000 0000 8946 5787, Institute for Research, Development and Innovation, , International Medical University, ; Kuala Lumpur, Malaysia
                [262 ]GRID grid.414102.2, Department of Health, ; Melbourne, Victoria Australia
                [263 ]GRID grid.5947.f, ISNI 0000 0001 1516 2393, Norwegian University of Science and Technology, ; Trondheim, Norway
                [264 ]GRID grid.42269.3b, ISNI 0000 0001 1203 7853, Faculty of Medicine, , Aleppo University, ; Aleppo, Syrian Arab Republic
                [265 ]GRID grid.512649.d, Global Health Literacy Academy, ; Risskov, Denmark
                [266 ]GRID grid.503447.1, ISNI 0000 0001 2189 9463, African Union, ; Addis Ababa, Ethiopia
                [267 ]GRID grid.17091.3e, ISNI 0000 0001 2288 9830, University of British Columbia, ; Vancouver, British Columbia Canada
                [268 ]Swiss Academies of Arts and Sciences, Bern, Switzerland
                [269 ]GRID grid.454294.a, ISNI 0000 0004 1773 2689, Indraprastha Institute of Information Technology, ; Delhi, India
                [270 ]GRID grid.470490.e, Centre of Excellence in Women and Child Health, , Aga Khan University, ; Nairobi, Kenya
                [271 ]Burnet Institute Myanmar, Yangon, Myanmar
                [272 ]Institute for Health Sciences Research (CNRST/IRSS), Nanoro, Burkina Faso
                [273 ]People’s Health Movement, Abomey-Calavi, Benin
                [274 ]Fundacion Octaedro, Quito, Ecuador
                [275 ]Khesar Gyalpo University of Medical Sciences of Bhutan, Thimphu, Bhutan
                [276 ]GRID grid.412881.6, ISNI 0000 0000 8882 5269, Antioquia University, ; Medellin, Colombia
                [277 ]Mälardalens University, Mälardalens, Sweden
                [278 ]GRID grid.5170.3, ISNI 0000 0001 2181 8870, Technical University of Denmark, ; Kongens Lyngby, Denmark
                [279 ]GRID grid.214458.e, ISNI 0000000086837370, University of Michigan Medical School, ; Ann Arbor, MI USA
                [280 ]GRID grid.410458.c, ISNI 0000 0000 9635 9413, Hospital Clínic, University of Barcelona, ; Barcelona, Spain
                [281 ]Bruegel Free University of Brussels, Brussels, Belgium
                [282 ]GRID grid.11135.37, ISNI 0000 0001 2256 9319, College of Environmental Sciences and Engineering, , Peking University, ; Beijing, China
                [283 ]GRID grid.7340.0, ISNI 0000 0001 2162 1699, University of Bath, ; Bath, UK
                [284 ]African Forum for Research and Education in Health, Kumasi, Ghana
                [285 ]GRID grid.508077.d, National Centre for Infectious Diseases, ; Singapore, Singapore
                [286 ]Gobierna Consulting Firm, Lima, Peru
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                Author information
                http://orcid.org/0000-0001-9618-2299
                http://orcid.org/0000-0002-4832-9564
                http://orcid.org/0000-0002-4986-2133
                http://orcid.org/0000-0003-0790-0506
                http://orcid.org/0000-0003-0875-7596
                http://orcid.org/0000-0002-6994-1891
                http://orcid.org/0000-0002-3869-615X
                http://orcid.org/0000-0001-5286-4044
                http://orcid.org/0000-0001-6203-1847
                http://orcid.org/0000-0002-0121-9683
                http://orcid.org/0000-0003-1793-6350
                http://orcid.org/0000-0003-2418-0037
                http://orcid.org/0000-0002-5095-748X
                http://orcid.org/0000-0003-4492-3256
                http://orcid.org/0000-0002-5964-8210
                http://orcid.org/0000-0002-6779-3151
                http://orcid.org/0000-0002-8074-4450
                Article
                5398
                10.1038/s41586-022-05398-2
                9646517
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                © The Author(s) 2022

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                : 19 May 2022
                : 29 September 2022
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