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      Inverting the structure–property map of truss metamaterials by deep learning

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          Significance

          More than a decade of research has been devoted to leveraging the rich mechanical playground of periodically assembled truss metamaterials. The enormous design space of manufacturable unit cells, however, has made the inverse design a challenge: How does one efficiently identify a complex truss that has given target properties? We answer this question by a data-driven method, which instantly (once trained, within milliseconds) generates not one but a variety of truss unit cells, whose effective response closely matches a given (fully anisotropic) stiffness tensor. Moreover, our framework to smoothly transition between different unit cells enables the design of lightweight structures with spatially varying, locally optimized properties, for applications from wave guiding to artificial bone.

          Abstract

          Inspired by crystallography, the periodic assembly of trusses into architected materials has enjoyed popularity for more than a decade and produced countless cellular structures with beneficial mechanical properties. Despite the successful and steady enrichment of the truss design space, the inverse design has remained a challenge: While predicting effective truss properties is now commonplace, efficiently identifying architectures that have homogeneous or spatially varying target properties has remained a roadblock to applications from lightweight structures to biomimetic implants. To overcome this gap, we propose a deep-learning framework, which combines neural networks with enforced physical constraints, to predict truss architectures with fully tailored anisotropic stiffness. Trained on millions of unit cells, it covers an enormous design space of topologically distinct truss lattices and accurately identifies architectures matching previously unseen stiffness responses. We demonstrate the application to patient-specific bone implants matching clinical stiffness data, and we discuss the extension to spatially graded cellular structures with locally optimal properties.

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          Most cited references61

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          Learning representations by back-propagating errors

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            The effect of pore geometry on the in vitro biological behavior of human periosteum-derived cells seeded on selective laser-melted Ti6Al4V bone scaffolds.

            The specific aim of this study was to gain insight into the influence of scaffold pore size, pore shape and permeability on the in vitro proliferation and differentiation of three-dimensional (3-D) human periosteum-derived cell (hPDC) cultures. Selective laser melting (SLM) was used to produce six distinct designed geometries of Ti6Al4V scaffolds in three different pore shapes (triangular, hexagonal and rectangular) and two different pore sizes (500 μm and 1000 μm). All scaffolds were characterized by means of two-dimensional optical microscopy, 3-D microfocus X-ray computed tomography (micro-CT) image analysis, mechanical compression testing and computational fluid dynamical analysis. The results showed that SLM was capable of producing Ti6Al4V scaffolds with a broad range of morphological and mechanical properties. The in vitro study showed that scaffolds with a lower permeability gave rise to a significantly higher number of cells attached to the scaffolds after seeding. Qualitative analysis by means of live/dead staining and scanning electron micrography showed a circular cell growth pattern which was independent of the pore size and shape. This resulted in pore occlusion which was found to be the highest on scaffolds with 500 μm hexagonal pores. Interestingly, pore size but not pore shape was found to significantly influence the growth of hPDC on the scaffolds, whereas the differentiation of hPDC was dependent on both pore shape and pore size. The results showed that, for SLM-produced Ti6Al4V scaffolds with specific morphological and mechanical properties, a functional graded scaffold will contribute to enhanced cell seeding and at the same time can maintain nutrient transport throughout the whole scaffold during in vitro culturing by avoiding pore occlusion.
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              Resilient 3D hierarchical architected metamaterials.

              Hierarchically designed structures with architectural features that span across multiple length scales are found in numerous hard biomaterials, like bone, wood, and glass sponge skeletons, as well as manmade structures, like the Eiffel Tower. It has been hypothesized that their mechanical robustness and damage tolerance stem from sophisticated ordering within the constituents, but the specific role of hierarchy remains to be fully described and understood. We apply the principles of hierarchical design to create structural metamaterials from three material systems: (i) polymer, (ii) hollow ceramic, and (iii) ceramic-polymer composites that are patterned into self-similar unit cells in a fractal-like geometry. In situ nanomechanical experiments revealed (i) a nearly theoretical scaling of structural strength and stiffness with relative density, which outperforms existing nonhierarchical nanolattices; (ii) recoverability, with hollow alumina samples recovering up to 98% of their original height after compression to ≥ 50% strain; (iii) suppression of brittle failure and structural instabilities in hollow ceramic hierarchical nanolattices; and (iv) a range of deformation mechanisms that can be tuned by changing the slenderness ratios of the beams. Additional levels of hierarchy beyond a second order did not increase the strength or stiffness, which suggests the existence of an optimal degree of hierarchy to amplify resilience. We developed a computational model that captures local stress distributions within the nanolattices under compression and explains some of the underlying deformation mechanisms as well as validates the measured effective stiffness to be interpreted as a metamaterial property.
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                Author and article information

                Journal
                Proc Natl Acad Sci U S A
                Proc Natl Acad Sci U S A
                pnas
                PNAS
                Proceedings of the National Academy of Sciences of the United States of America
                National Academy of Sciences
                0027-8424
                1091-6490
                30 December 2021
                4 January 2022
                30 December 2021
                : 119
                : 1
                : e2111505119
                Affiliations
                [1] aMechanics & Materials Laboratory, Department of Mechanical and Process Engineering, Eidgenössische Technische Hochschule Zürich , 8092 Zürich, Switzerland;
                [2] bDepartment of Materials Science and Engineering, Delft University of Technology , 2628 CD Delft, The Netherlands
                Author notes
                1To whom correspondence may be addressed. Email: dmk@ 123456ethz.ch .

                Edited by Yonggang Huang, Northwestern University, Glencoe, IL; received June 22, 2021; accepted November 15, 2021

                Author contributions: J.-H.B., S.K., and D.M.K. designed research; J.-H.B. performed research; B.T. and R.N.G. contributed analytic tools; J.-H.B. analyzed data; and J.-H.B., S.K., and D.M.K. wrote the paper.

                Author information
                https://orcid.org/0000-0003-3343-1977
                https://orcid.org/0000-0003-1602-8641
                https://orcid.org/0000-0002-4404-2910
                https://orcid.org/0000-0002-9112-6615
                Article
                202111505
                10.1073/pnas.2111505119
                8740766
                34983845
                3ae9fdde-2a89-4927-8e01-7a05d7c768a8
                Copyright © 2021 the Author(s). Published by PNAS.

                This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY).

                History
                : 15 November 2021
                Page count
                Pages: 9
                Categories
                416
                Physical Sciences
                Engineering

                inverse design,truss,metamaterial,deep learning,stiffness
                inverse design, truss, metamaterial, deep learning, stiffness

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