Airway management for general anesthesia in patients with rheumatic diseases can be
very challenging because of changes related to the disease, especially in temporomandibular
joints and the cervical spine.
In this case airway and neck assessment is crucial; atlanto-axial subluxation can
be detected and there is a potential risk of spinal cord damage when performing airway
management. For most cases awake fibreoptic intubation may be required for airway
management, which is considered as the standard approach [1].
Changes in the cervical spine include sclerosis, discopathy, and instability of vertebral
joints with the possibility of subluxations. The conditions may be complicated by
previous surgery for stabilization of the cervical spine and discopathy treatment.
Changes in joints can be related to several rheumatoid diseases. For airway management
inflammation of temporomandibular joints and vertebral joints in the cervical spine
is important.
For airway management, the implication will be especially the reduction of mouth opening
and a commonly occurring cervical stiffness that make both the intubation procedures
and the positioning of head and neck difficult. For evaluation one may use the Mallampati
score, mouth opening and mandible protrusion as preoperative predictors of temporomandibular
dysfunction.
Cricoarytenoid dysfunction is another factor influencing difficulties related to airway
management. The larynx may be affected in approximately 80% of patients. The symptoms
may be presented as foreign body sensation in the oropharynx, dysphagia, dyspnea,
hoarseness, stridor, and also by airway obstruction. As possible diagnosis during
visualization of the larynx may reveal cricoarytenoid and vocal cord dysfunction during
inspiration.
For patients with this disease fiberoptic nasoendoscopy is recommended and the use
of a tracheal tube with a small diameter that can provide appropriate ventilation.
It is important to avoid trauma of the laryngeal structures. For safe extubation the
removal of the tracheal tube should take place in an appropriate environment prepared
for emergencies. In some cases even preventive preoperative tracheostomy should be
considered [2].
The use of fiber optic bronchoscopy is recommended in such cases, because it allows
adequate access to the airways with minimal cervical mobilization. Awake intubation
should be considered but it requires a suitably trained anesthesiologist, with minimal
sedation.
The occurrence of ankylosis of the temporomandibular joint poses additional risk during
airway management for anesthesia, because the occurrence of small mouth openings to
less than 2 cm is possible. In these cases the use of a flexible fiber optic bronchoscope
is recommended.
As an alternative to endotracheal intubation the use of a laryngeal mask airways can
be considered, which provides airway protections with less airway trauma. However,
there are reports that its use can worsen the symptoms of cricoarytenoid involvement.
Some authors suggest for preanesthesia airway evaluation indirect laryngoscopy.
The atlanto-axial joint is commonly affected. Acute subluxation may cause spinal cord
compression and/or compression of the vertebral arteries leading to quadriparesis
or sudden death during airway management attempts.
The temporomandibular joint (TMJ) may be involved, causing limitation of mouth opening
and rendering direct laryngoscopy impossible.
For general anesthesia the airway may be managed in several ways: the laryngeal mask
airway (LMA) can be effectively used [3]. However, it may be difficult to insert an
LMA if the angle between the oral and pharyngeal axes at the back of the tongue is
less than 90 degrees. Retrograde intubation may also be considered.
The choice to perform tracheal intubation for general anesthesia should depend on
an assessment of the risks of gastric aspiration, and the type and duration of surgery.
As tracheal intubation is indicated, it must be achieved without causing further injury
to a potentially unstable cervical spine. The manipulation of the neck during airway
management attempts can lead to neurological deterioration, tetraplegia and even sudden
death and thus should be avoided. When trying to position the patient’s head in recommended
“sniffing” position for direct laryngoscopy, when the head is hyperextended on a flexed
neck it can result in exacerbation of the anterior atlanto-axial subluxation with
resultant neurological injury. Therefore during conventional laryngoscopy and neck
manipulation special care must be considered, even without overt cervical spine instability.
An intubating LMA (ILMA) may be used to achieve blind endotracheal intubation with
minimal cervical spine movement, but the poor success rate without the use of fiber
optics and the great amount of force that may be exerted on the posterior wall of
the pharynx at C2–C3 make the ILMA not recommended as a primary method of intubation
[4].
Fibreoptic intubation is proved to provide the safety of airway management in an awake
intubation method and is highly recommended. These efforts are employed to prevent
hyperextension of the neck, a common occurrence in airway maneuvers. Unfortunately,
an awake fibreoptic intubation often is performed not without problems and depends
on the skill of the operator [5].
A surgical tracheostomy performed under local anesthesia can be considered a method
of securing the airway of patients with cricoarytenoid involvement. However, potential
difficulties with this method include the presence of an extreme fixed flexion deformity
with little or no access to the trachea, tracheal deviation and patient distress [6].
As mentioned above, the method of first choice for airway management in patients with
rheumatoid diseases scheduled for general anesthesia still fiberoptic intubation is
considered. Unfortunately fiberoptic intubation requires adequate equipment and skills
of the operator. There is an alternative for fiberoptic intubation if endotracheal
intubation is recommended: videolaryngoscopes and rigid optic intubation stylets.
Videolaryngoscopes are easier to use with the same effectiveness of intubation as
fibroscopes. Most anesthesiologists can effectively use videolaryngoscopes after a
short training period, in contrast to fiberoptic intubation, which requires long training.
Videolaryngoscopes are easier because they can be used similarly to standard laryngoscopes.
The Glidescope (GS) (Saturn Biomedical System Inc., Burnaby, BC, Canada) is reported
as a useful device that improved visualization of the larynx and facilitated naso-tracheal
intubation. The GS improved the laryngoscopic view in all patients and nasal intubation
was successful in most of the patients. The main limitation of the GS is the resistance
encountered during advancement of the tracheal tube [7].
To overcome the obstacles that may occur in a difficult intubation, an endotracheal
introducer able to facilitate the passage of the endotracheal tube through the vocal
cords into the trachea may be useful [8].
A novel technique of endotracheal intubation is used for the successful airway management
during the surgical treatment in patients with temporomandibular joint ankylosis with
the assistance of a fiberscope and GlideScope videolaryngoscope [9]. This technique
avoids complications such as trauma to soft tissue structures surrounding the glottis
during the passage of the tube over the fiberscope. It gives a clear view of the tube
and its cuff position during intubation. Other videolaryngoscopes can also be used
such as the McGrath videolaryngoscope for awake intubation in patients with severe
ankylosing spondylitis [10].
Our experience shows that the McGrath Mac videolaryngoscope (Medtronic, USA) can be
used successfully in patients with rheumatoid diseases. We managed a few cases of
patients with ankylosing spondylitis using the McGrath Mac videolaryngoscope as alternative
to fiberoptic intubation. In the case presented in Figures 1 and 2 the videolaryngoscope
allowed for face-to-face approach technique, similarly to fiberoptic intubation.
Fig. 1
Fig. 2
Rigid optic intubation stylets can be used similarly to standard intubation stylets
so it is easier for most anesthesiologists to learn fast how to operate them. They
are especially useful in patients with limited mouth opening.
In summary, airway management in patients with rheumatic diseases requires an individualized
approach plan. The choice of method is based on the patient’s condition, airway evaluation,
available equipment, skills of the operator and predicted postoperative airway challenges.
New devices such as videolaryngoscopes can provide an easy learning curve, with comparable
effectiveness and safety to standard fiberoptic intubation.