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      Hospital admissions for respiratory tract infections in children aged 0-5 years for 2017/2023

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      medRxiv

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          Abstract

          Aim

          To compare hospital admissions across common respiratory tract infections (RTI) in 2017-21, and project possible hospital admissions for the RTIs among children aged 0-12 months and 1-5 years in 2022 and 2023.

          Methods

          In 644 885 children aged 0-12 months and 1-5 years, we plotted the observed monthly number of RTI admissions (upper- and lower RTI, influenza, respiratory syncytial virus (RSV), and COVID-19) from January 1 st, 2017 until October 31 st, 2021. We also plotted the number of RTI admissions with a need for respiratory support. We used the observed data to project four different scenarios of RTI admissions for the rest of 2021 until 2023, with different impacts on hospital wards: 1) “Business as usual”, 2) “Continuous lockdown”, 3) “Children’s immunity debt”, and 4) “Maternal and child immunity debt”.

          Results

          By October 31 st, 2021, the number of simultaneous RTI admissions had exceeded the numbers usually observed at the typical season peak in January, i.e. ∼900. Based on our observed data and assuming that children and their mothers (who transfer antibodies to the very youngest) have not been exposed to RTI over the last one and a half years, our scenarios suggest that hospitals should be prepared to handle two to three times as many RTI admissions, and two to three times as many RTI admissions requiring respiratory support among 0-5-year-olds as normal, from November 2021 to April 2022.

          Conclusion

          Scenarios with immunity debt suggest that pediatric hospital wards and policy makers should plan for extended capacity.

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          Author and article information

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          Journal
          medRxiv
          November 24 2021
          Article
          10.1101/2021.11.22.21266564
          333950fb-2aed-45c7-8b7b-c33965133f01
          © 2021
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