0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Exploring neurocognitive features in adolescents and young adults with anorexia nervosa: Evidence from a longitudinal study

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Objective

          We aimed to evaluate longitudinal changes in set‐shifting and central coherence in a predominantly adolescent cohort with anorexia nervosa (AN) and to explore whether these factors predict long‐term eating disorder outcomes.

          Method

          Ninety‐two female patients with AN (mean age: 16.2, range: 13–21 years) completed neurocognitive tests (Rey Complex Figure Test, Adapted Version of the Wisconsin Card Sorting Test) before and after 12 months of psychotherapeutic treatment ( n = 45 Maudsley AN Treatment, MANTRa; n = 47 standard psychotherapy; groups not randomised). Eating disorder severity was assessed at baseline, after 6, 12 and 18 months.

          Results

          Central coherence (indicated by an increase in the Rey Figure Style Index) and set‐shifting (indicated by a reduction in the percentage of perseverative errors) significantly improved over the course of treatment, with similar outcomes across groups. Lower central coherence was associated with higher eating disorder severity. Individuals with lower baseline set‐shifting ability tended to have worse eating disorder outcomes in the long‐term. However, this trend did not reach statistical significance in a multilevel linear mixed model.

          Conclusions

          Neurocognitive difficulties in adolescents and young adults with AN can improve after treatment. Interventions specifically addressing flexibility in thinking and behaviour may contribute to treatment success.

          Highlights

          • Central coherence and set‐shifting significantly improved over the course of treatment, with similar outcomes across groups (MANTRa treatment vs. standard psychotherapy).

          • Lower central coherence was associated with higher eating disorder severity.

          • There was a trend towards lower set‐shifting being associated with worse eating disorder outcomes in the long‐term, indicating that interventions addressing cognitive flexibility may contribute to treatment success.

          Related collections

          Most cited references46

          • Record: found
          • Abstract: not found
          • Article: not found

          Fitting Linear Mixed-Effects Models Usinglme4

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            A modified card sorting test sensitive to frontal lobe defects.

            H Nelson (1976)
            Milner's (1963) report of impaired performance on the Wisconsin Card Sorting Test (WCST) in a group of patients with frontal lobe lesions suggested that this test might be a useful one in the investigation of individual patients with suspected brain lesions. However, for many of our older hospital population the WCST was found to be too difficult and distressing, and also the inherent ambiguities associated with certain responses limited the test's usefulness for research purposes. Therefore, a simpler and less ambiguous modification was devised (MCS) and a new method of measuring perseverative errors proposed. In a group of 53 patients with unilateral cerebral lesions, those with frontal lobe lesions performed less well with the MCST and made a higher proportion of perseverative errors than those with lesions elsewhere: there were no laterality effects in either frontal or non-frontal groups. The usefulness of the MCST for detecting frontal lobe lesions in individual patients was established, and the use of cut-off scores briefly discussed.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Perzentile für den Body-mass-Index für das Kindes- und Jugendalter unter Heranziehung verschiedener deutscher Stichproben

                Bookmark

                Author and article information

                Contributors
                gudrun.wagner@meduniwien.ac.at
                Journal
                Eur Eat Disord Rev
                Eur Eat Disord Rev
                10.1002/(ISSN)1099-0968
                ERV
                European Eating Disorders Review
                John Wiley and Sons Inc. (Hoboken )
                1072-4133
                1099-0968
                12 July 2024
                January 2025
                : 33
                : 1 ( doiID: 10.1002/erv.v33.1 )
                : 20-34
                Affiliations
                [ 1 ] Eating Disorder Unit Department of Child and Adolescent Psychiatry Medical University of Vienna Vienna Austria
                [ 2 ] Department of Neurology and Psychiatry of Childhood and Adolescence Clinical Centre Klagenfurt Klagenfurt am Wörthersee Austria
                [ 3 ] Institute of Psychiatry Psychology & Neuroscience King's College London London UK
                Author notes
                [*] [* ] Correspondence

                Gudrun Wagner, Eating Disorder Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Waehringer Guertel 18‐20, Vienna 1090, Austria.

                Email: gudrun.wagner@ 123456meduniwien.ac.at

                Author information
                https://orcid.org/0000-0001-7358-4842
                https://orcid.org/0000-0002-7087-6134
                https://orcid.org/0000-0002-7374-4559
                https://orcid.org/0000-0003-0992-6865
                https://orcid.org/0000-0003-0709-0080
                https://orcid.org/0000-0001-9746-8141
                https://orcid.org/0000-0002-0492-2286
                https://orcid.org/0000-0002-8194-4075
                https://orcid.org/0000-0003-1335-1937
                https://orcid.org/0000-0001-9053-998X
                https://orcid.org/0000-0002-4845-9684
                Article
                ERV3127
                10.1002/erv.3127
                11617805
                38995317
                32f16b2d-f363-4781-941b-3ffbf12bfe12
                © 2024 The Author(s). European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

                History
                : 26 May 2024
                : 26 February 2024
                : 30 June 2024
                Page count
                Figures: 1, Tables: 4, Pages: 15, Words: 9080
                Funding
                Funded by: Gemeinsame Gesundheitsziele – Pharma Master Agreement – project code: 99901006800
                Categories
                Research Article
                Research Article
                Custom metadata
                2.0
                January 2025
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.5.1 mode:remove_FC converted:05.12.2024

                Clinical Psychology & Psychiatry
                adolescents,anorexia nervosa,central coherence,maudsley model,set‐shifting

                Comments

                Comment on this article