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      Production and Status of Bacterial Cellulose in Biomedical Engineering

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          Abstract

          Bacterial cellulose (BC) is a highly pure and crystalline material generated by aerobic bacteria, which has received significant interest due to its unique physiochemical characteristics in comparison with plant cellulose. BC, alone or in combination with different components (e.g., biopolymers and nanoparticles), can be used for a wide range of applications, such as medical products, electrical instruments, and food ingredients. In recent years, biomedical devices have gained important attention due to the increase in medical engineering products for wound care, regeneration of organs, diagnosis of diseases, and drug transportation. Bacterial cellulose has potential applications across several medical sectors and permits the development of innovative materials. This paper reviews the progress of related research, including overall information about bacterial cellulose, production by microorganisms, mechanisms as well as BC cultivation and its nanocomposites. The latest use of BC in the biomedical field is thoroughly discussed with its applications in both a pure and composite form. This paper concludes the further investigations of BC in the future that are required to make it marketable in vital biomaterials.

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          Microfibrillated cellulose and new nanocomposite materials: a review

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            The fluorescent toolbox for assessing protein location and function.

            Advances in molecular biology, organic chemistry, and materials science have recently created several new classes of fluorescent probes for imaging in cell biology. Here we review the characteristic benefits and limitations of fluorescent probes to study proteins. The focus is on protein detection in live versus fixed cells: determination of protein expression, localization, activity state, and the possibility for combination of fluorescent light microscopy with electron microscopy. Small organic fluorescent dyes, nanocrystals ("quantum dots"), autofluorescent proteins, small genetic encoded tags that can be complexed with fluorochromes, and combinations of these probes are highlighted.
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              Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig.

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                Author and article information

                Journal
                Nanomaterials (Basel)
                Nanomaterials (Basel)
                nanomaterials
                Nanomaterials
                MDPI
                2079-4991
                04 September 2017
                September 2017
                : 7
                : 9
                : 257
                Affiliations
                [1 ]Department of Bioprocess Technology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; mona_moniri6@ 123456yahoo.com (M.M.); amin.broomandm@ 123456yahoo.com (A.B.M.); arbarif@ 123456upm.edu.my (A.B.A.)
                [2 ]Young Researcher and Elite Club, Sabzevar Branch, Islamic Azad University, Sabzevar, Iran
                [3 ]Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; raha@ 123456upm.edu.my
                [4 ]Bioprocessing and Biomanufacturing Research Center, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
                [5 ]Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; zuhainis@ 123456upm.edu.my
                [6 ]Institute of Tropical Forestry and Forest Products, Univerciti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
                [7 ]Young Research and Elite Club, Parand Branch, Islamic Azad University, Parand, Iran; navaderimohammad@ 123456yahoo.com
                Author notes
                [* ]Correspondence: azisusan@ 123456gmail.com (S.A.); farizan@ 123456upm.edu.my (R.M.); Tel.: +60-1-7622-8029 (S.A.); +60-1-3263-6029 (R.M.)
                Author information
                https://orcid.org/0000-0002-3245-5427
                Article
                nanomaterials-07-00257
                10.3390/nano7090257
                5618368
                32962322
                230b8049-edf9-49fd-b56b-76e0c6110798
                © 2017 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 29 June 2017
                : 01 September 2017
                Categories
                Review

                bacteria cellulose,bacteria nanocellulose,wound dressing,scaffolds,biosensors

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