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      How to calculate sample size in animal studies?

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          Abstract

          Calculation of sample size is one of the important component of design of any research including animal studies. If a researcher select less number of animals it may lead to missing of any significant difference even if it exist in population and if more number of animals selected then it may lead to unnecessary wastage of resources and may lead to ethical issues. In this article, on the basis of review of literature done by us we suggested few methods of sample size calculations for animal studies.

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          Most cited references11

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          Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research.

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            Some Practical Guidelines for Effective Sample Size Determination

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              An introduction to power and sample size estimation.

              The importance of power and sample size estimation for study design and analysis.
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                Author and article information

                Journal
                J Pharmacol Pharmacother
                J Pharmacol Pharmacother
                JPP
                Journal of Pharmacology & Pharmacotherapeutics
                Medknow Publications & Media Pvt Ltd (India )
                0976-500X
                0976-5018
                Oct-Dec 2013
                : 4
                : 4
                : 303-306
                Affiliations
                [1] Department of Pharmacology, GMERS Medical College, Patan, Government Medical College, Surat, Gujarat, India
                Author notes
                Address for correspondence: Jaykaran Charan, Department of Pharmacology, Government Medical College, Surat, Gujarat, India. E-mail: drjaykaran@ 123456yahoo.co.in
                Article
                JPP-4-303
                10.4103/0976-500X.119726
                3826013
                24250214
                1f8d2bdf-c6d8-412e-991c-dc36f434cd20
                Copyright: © Journal of Pharmacology and Pharmacotherapeutics

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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                Categories
                Educational Forum

                Pharmacology & Pharmaceutical medicine
                alpha error,animal studies,power,sample size
                Pharmacology & Pharmaceutical medicine
                alpha error, animal studies, power, sample size

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