Effects of SARS-CoV-2 infection on human reproduction

Author(s): Ming Yang ¹ ^, ³ ^, ⁵ ^, ⁷ , Jing Wang ¹ ^, ² , Yidong Chen ¹ ^, ³ ^, ⁵ ^, ⁷ , Siming Kong ¹ ^, ³ ^, ⁵ ^, ⁷ , Jie Qiao ¹ ^, ² ^, ³ ^, ⁴ ^, ⁵ ^, ⁶ ^, ⁷

Publication date (Electronic): 18 May 2021

Journal: Journal of Molecular Cell Biology

Publisher: Oxford University Press

Keywords: COVID-19, SARS-CoV-2, reproduction, vertical transmission

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Abstract

The worldwide infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) impacts human health and life on multiple levels. People infected with SARS-CoV-2 suffer from physical disorders and psychological distress. At present, no direct evidence indicates that SARS-CoV-2 negatively influences human reproduction, and the possibility that gametes and embryos are affected requires further investigation. To evaluate the potential effects of SARS-CoV-2 infection on human reproduction and fetal health, this review summarizes the basic and clinical research of SARS-CoV-2 on reproduction up to date, hoping to offer guidance and advice to people at reproductive age and provide clues for the prevention and treatment of associated diseases.

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Author and article information

Journal

Journal ID (nlm-ta): J Mol Cell Biol

Journal ID (iso-abbrev): J Mol Cell Biol

Journal ID (publisher-id): jmcb

Title: Journal of Molecular Cell Biology

Publisher: Oxford University Press

ISSN (Print): 1674-2788

ISSN (Electronic): 1759-4685

Publication date (Electronic): 18 May 2021

Electronic Location Identifier: mjab025

Affiliations

[1 ]Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology , Beijing 100191, China

[2 ] National Clinical Research Center for Obstetrics and Gynecology , Beijing 100191, China

[3 ] Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education , Beijing 100191, China

[4 ] Beijing Advanced Innovation Center for Genomics , Beijing 100871, China

[5 ] Peking-Tsinghua Center for Life Sciences, Peking University , Beijing 100871, China

[6 ]Research Units of Comprehensive Diagnosis and Treatment of Oocyte Maturation Arrest, Peking University , Beijing 100871, China

[7 ]Academy for Advanced Interdisciplinary Studies, Peking University , Beijing 100871, China

Author notes

These authors contributed equally to this work.

Correspondence to: Jie Qiao, E-mail: jie.qiao@ 123456263.net

Article

Publisher ID: mjab025

DOI: 10.1093/jmcb/mjab025

PMC ID: 8194633

PubMed ID: 34003284

SO-VID: 1aab5eec-2a8e-413c-942e-2017258d5738

License:

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

History

Date received : 09 October 2020

Date revision received : 18 March 2021

Date accepted : 23 March 2021

Page count

Pages: 17

Custom metadata

edited-state accepted-manuscript

article-lifecycle PAP

Keywords: covid-19,sars-cov-2,reproduction,vertical transmission

Data availability:

Keywords: covid-19, sars-cov-2, reproduction, vertical transmission

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