Daniel J. Rawle:
ORCID: https://orcid.org/0000-0001-7248-0101
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: SupervisionRole: ValidationRole:
VisualizationRole: Writing – original draftRole: Writing – review & editing
Thuy T. Le:
ORCID: https://orcid.org/0000-0001-9134-0104
Role: Investigation
Troy Dumenil: Role: Data curationRole: Formal analysisRole: Visualization
Kexin Yan: Role: Investigation
Bing Tang: Role: Investigation
Wilson Nguyen:
ORCID: https://orcid.org/0000-0002-5789-4928
Role: Formal analysis
Daniel Watterson:
ORCID: https://orcid.org/0000-0001-5957-2853
Role: InvestigationRole: ResourcesRole: Visualization
Naphak Modhiran:
ORCID: https://orcid.org/0000-0003-3205-4970
Role: InvestigationRole: ResourcesRole: Visualization
Jody Hobson-Peters: Role: InvestigationRole: Resources
Cameron Bishop:
ORCID: https://orcid.org/0000-0002-5710-9942
Role: Visualization
Andreas Suhrbier:
ORCID: https://orcid.org/0000-0001-8986-9025
Role: Data curationRole: Formal analysisRole: Funding acquisitionRole: MethodologyRole:
Project administrationRole: ResourcesRole: SupervisionRole: VisualizationRole: Writing
– review & editing
Benhur Lee: Role: Editor
Journal ID (nlm-ta): PLoS Pathog
Journal ID (iso-abbrev): PLoS Pathog
Journal ID (publisher-id): plos
Title:
PLoS Pathogens
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7366
ISSN
(Electronic):
1553-7374
Publication date
(Electronic):
2
July
2021
Publication date Collection:
July
2021
Volume: 17
Issue: 7
Electronic Location Identifier: e1009723
Affiliations
[1
]
Immunology Department, QIMR Berghofer Medical Research Institute, Brisbane, Queensland,
Australia
[2
]
School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia,
Queensland, Australia
[3
]
Australian Infectious Disease Research Centre, GVN Center of Excellence, Brisbane,
Queensland, Australia
Icahn School of Medicine at Mount Sinai, UNITED STATES
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PPATHOGENS-D-21-00524
DOI: 10.1371/journal.ppat.1009723
PMC ID: 8282004
PubMed ID: 34214142
SO-VID: 18fe8c8c-d4b9-4fc8-9268-451c7a6d8c55
Copyright © © 2021 Rawle et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by:
Clive Berghofer and Brazil Family Foundation
Award ID: Philanthropic
Award Recipient
:
ORCID: https://orcid.org/0000-0001-8986-9025
Andreas Suhrbier
Funded by:
clive berghofer and the brazil family foundation
Award ID: Philanthropic
Award Recipient
:
ORCID: https://orcid.org/0000-0001-7248-0101
Daniel J. Rawle
Funded by:
funder-id http://dx.doi.org/10.13039/501100000925, National Health and Medical Research Council;
Award ID: APP1173880
Award Recipient
:
ORCID: https://orcid.org/0000-0001-8986-9025
Andreas Suhrbier
Funded by:
australian infectious diseases research centre
Award ID: intramural seed grant
We thank Clive Berghofer and the Brazil Family Foundation (and many others) for their
generous philanthropic donations to support SARS-CoV-2 research at QIMR Berghofer
MRI (
https://www.qimrberghofer.edu.au/) (intramural grants awarded to A.S. and D.J.R). The project was also partly funded
by an intramural seed grant from the Australian Infectious Diseases Research Centre
(
https://aidrc.org.au/) awarded to A.S. A.S. holds an Investigator grant from the National Health and Medical
Research Council (NHMRC,
https://www.nhmrc.gov.au/) of Australia (APP1173880). The funders had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
RNA viruses
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
SARS CoV 2
Subject:
Biology and life sciences
Subject:
Microbiology
Subject:
Medical microbiology
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
SARS CoV 2
Subject:
Medicine and health sciences
Subject:
Pathology and laboratory medicine
Subject:
Pathogens
Subject:
Microbial pathogens
Subject:
Viral pathogens
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
SARS CoV 2
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral pathogens
Subject:
Coronaviruses
Subject:
SARS coronavirus
Subject:
SARS CoV 2
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Model Organisms
Subject:
Mouse Models
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Mouse Models
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Animal Models
Subject:
Mouse Models
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Virology
Subject:
Viral Replication
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
RNA viruses
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Animal Models of Disease
Subject:
Animal Models of Infection
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Animal Models of Infection
Subject:
Medicine and Health Sciences
Subject:
Medical Conditions
Subject:
Infectious Diseases
Subject:
Viral Diseases
Subject:
Covid 19
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Respiratory System
Subject:
Bronchioles
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Respiratory System
Subject:
Bronchioles
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Inflammation
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Inflammation
Subject:
Medicine and Health Sciences
Subject:
Clinical Medicine
Subject:
Signs and Symptoms
Subject:
Inflammation