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      Crowdsourcing in medical research: concepts and applications

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          Abstract

          Crowdsourcing shifts medical research from a closed environment to an open collaboration between the public and researchers. We define crowdsourcing as an approach to problem solving which involves an organization having a large group attempt to solve a problem or part of a problem, then sharing solutions. Crowdsourcing allows large groups of individuals to participate in medical research through innovation challenges, hackathons, and related activities. The purpose of this literature review is to examine the definition, concepts, and applications of crowdsourcing in medicine. This multi-disciplinary review defines crowdsourcing for medicine, identifies conceptual antecedents (collective intelligence and open source models), and explores implications of the approach. Several critiques of crowdsourcing are also examined. Although several crowdsourcing definitions exist, there are two essential elements: (1) having a large group of individuals, including those with skills and those without skills, propose potential solutions; (2) sharing solutions through implementation or open access materials. The public can be a central force in contributing to formative, pre-clinical, and clinical research. A growing evidence base suggests that crowdsourcing in medicine can result in high-quality outcomes, broad community engagement, and more open science.

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          Most cited references63

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          Open Source Software and the “Private-Collective” Innovation Model: Issues for Organization Science

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            Crowdsourcing as a Model for Problem Solving: An Introduction and Cases

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              AggNet: Deep Learning From Crowds for Mitosis Detection in Breast Cancer Histology Images

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                Author and article information

                Contributors
                Journal
                PeerJ
                PeerJ
                PeerJ
                PeerJ
                PeerJ
                PeerJ Inc. (San Diego, USA )
                2167-8359
                12 April 2019
                2019
                : 7
                : e6762
                Affiliations
                [1 ]Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill , Chapel Hill, NC, USA
                [2 ]Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, University of London , London, UK
                [3 ]Social Entrepreneurship to Spur Health (SESH) Global , Guangzhou, China
                [4 ]Department of Social Medicine, University of North Carolina at Chapel Hill , Chapel Hill, NC, USA
                [5 ]Department of STD Control, Dermatology Hospital of Southern Medical University , Guangzhou, China
                [6 ]Kenan-Flagler School of Business, University of North Carolina at Chapel Hill , Chapel Hill, NC, USA
                Article
                6762
                10.7717/peerj.6762
                6463854
                30997295
                17ab9c77-3532-4765-90db-917596ee6e43
                © 2019 Tucker et al.

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

                History
                : 5 November 2018
                : 11 March 2019
                Funding
                Funded by: National Key Research and Development Program of China
                Award ID: 2017YFE0103800
                Funded by: National Institutes of Health
                Award ID: NIAID 1R01AI114310-01, NIAID K24AI143471, NICHD UG3HD096929
                Funded by: UNC Center for AIDS Research
                Award ID: NIAID 5P30AI050410
                Funded by: North Carolina Translational & Clinical Sciences Institute
                Award ID: 1UL1TR001111
                This study received support from the National Key Research and Development Program of China (2017YFE0103800), the National Institutes of Health (NIAID 1R01AI114310-01, NIAID K24AI143471, NICHD UG3HD096929), the UNC Center for AIDS Research (NIAID 5P30AI050410), and the North Carolina Translational & Clinical Sciences Institute (1UL1TR001111). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Global Health
                Health Policy
                Internal Medicine
                Legal Issues
                Science and Medical Education

                crowdsourcing,theory,literature review,collective intelligence,open source model

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