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      Decreased functional connectivity and disrupted neural network in the prefrontal cortex of affective disorders: A resting-state fNIRS study.

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          Abstract

          Affective disorders (AD) have been conceptualized as neural network-level diseases. In this study, we utilized functional near infrared spectroscopy (fNIRS) to investigate the spontaneous hemodynamic activities in the prefrontal cortex (PFC) of the AD patients with or without medications.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): J Affect Disord
          Title: Journal of affective disorders
          Publisher: Elsevier BV
          ISSN (Electronic): 1573-2517
          ISSN (Print): 0165-0327
          Publication date (Electronic): Oct 15 2017
          Volume: 221
          Affiliations
          [1 ] Centre for Optical and Electromagnetic Research, South China Academy of Advanced Optoelectronics, South China Normal University (SCNU), Guangzhou 510006, PR China. Electronic address: huilin.zhu@m.scnu.edu.cn.
          [2 ] Centre for Optical and Electromagnetic Research, South China Academy of Advanced Optoelectronics, South China Normal University (SCNU), Guangzhou 510006, PR China.
          [3 ] The Research Center of Psychological Counseling, South China Normal University (SCNU), Guangzhou 510631, PR China.
          [4 ] The Department of Clinical Psychology, Guangzhou Brain Hospital (Guangzhou Huiai Hospital, Affiliated Brain Hospital of Guangzhou Medical University), Guangzhou 510170, PR China.
          [5 ] Centre for Optical and Electromagnetic Research, South China Academy of Advanced Optoelectronics, South China Normal University (SCNU), Guangzhou 510006, PR China; School of Psychology, South China Normal University (SCNU), Guangzhou 510631, PR China.
          Article
          Publisher Item ID: S0165-0327(16)32279-0
          DOI: 10.1016/j.jad.2017.06.024
          PubMed ID: 28645025
          SO-VID: 123fbc40-f296-4139-8891-4a5e306ebd99
          History

          Keywords: Affective disorders,Depression,Functional near infrared spectroscopy,Neural networks,Resting-state functional connectivity
          Data availability:
          Keywords: Affective disorders, Depression, Functional near infrared spectroscopy, Neural networks, Resting-state functional connectivity

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