Real-life experience with ceftolozane/tazobactam in Canada: results from the CLEAR (Canadian LEadership on Antimicrobial Real-life usage) registry.

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Abstract

Ceftolozane/tazobactam is a cephalosporin/β-lactamase inhibitor combination with activity against Gram-negative bacilli. Here we report the use of ceftolozane/tazobactam in Canada using a national registry.

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Author and article information

Journal

Journal ID (iso-abbrev): J Glob Antimicrob Resist

Title: Journal of global antimicrobial resistance

Publisher: Elsevier BV

ISSN (Electronic): 2213-7173

ISSN (Print): 2213-7165

Publication date (Electronic): Jun 2021

Volume: 25

Affiliations

[1 ] Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: ggzhanel@pcsinternet.ca.

[2 ] Department of Pharmacy, London Health Sciences Centre, London, Ontario, Canada.

[3 ] Department of Medical Microbiology and Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

[4 ] Department of Pharmacy, Royal University Hospital, Saskatoon, Saskatchewan, Canada.

[5 ] Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

[6 ] Department of Pharmacy, Hamilton Health Sciences Centre, Hamilton, Ontario, Canada.

[7 ] Department of Pharmacy, Ottawa Hospital, Ottawa, Ontario, Canada.

[8 ] Section of Infectious Diseases, William Osler Health System, Brampton, Ontario, Canada.

[9 ] Pharmacy Department, CIUSSS de l'Est-de-l'Île-de-Montréal, Montreal, Québec, Canada.

[10 ] Section of Infectious Diseases, Department of Medicine, The Moncton Hospital, New Brunswick, Canada.

[11 ] Department of Pharmacy, St Boniface Hospital, Winnipeg, Manitoba, Canada.

[12 ] Department of Pharmacy, Sainte-Croix Hospital, Drummondville, Québec, Canada.

[13 ] Infectious Diseases Clinic, Department of Health Sciences, University of Genoa and Policlinico San Marino IRCCS, Genoa, Italy.

Article

Publisher Item ID: S2213-7165(21)00095-3

DOI: 10.1016/j.jgar.2021.03.025

PubMed ID: 33984530

SO-VID: 0e2d9df6-4de9-4c62-b4fe-7f96291d3cba

History

Keywords: Pneumonia,Adverse effect,Bacteraemia,CLEAR,Ceftolozane/tazobactam,Efficacy

Data availability:

Keywords: Pneumonia, Adverse effect, Bacteraemia, CLEAR, Ceftolozane/tazobactam, Efficacy

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