Clinical research: A personal perspective

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Abstract

Research ought to be inculcated as an attitude during the formative years of every health-care professional. The core elements of research are curiosity, observation, reasoning, and experimentation. These suggestions are supported with suitable examples. Medical advisers in the pharmaceutical industry are in a unique position to act as facilitators of such a process. The tools they can use are also suggested.

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Most cited references 8

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Severe envenoming by the Indian red scorpion Mesobuthus tamulus: the use of prazosin therapy.

H. S. Bawaskar, P Bawaskar (1996)

We describe the clinical course and outcome in 46 victims of severe scorpion envenoming treated with prazosin (P), and compare them with earlier patients treated with conventional therapy (C) (n = 45) and nifepidine (N) (n = 28). The incidence of complicating left ventricular failure was 29% for C, 35% for N and 6.5% for P; that of acute pulmonary oedema was 46% for C, 14% for N and zero for P; mortality was 25% for C, 3.5% for N and zero for P. Although this is a historical study, prazosin appears to significantly reduce morbidity and shorten recovery time. Experience in other countries suggests that antivenom is helpful in controlling many of these problems, but in rural India serotherapy remains largely unavailable, and prazosin is a mainstay of treatment.

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Kapil S. Kulkarni, A Nanivadekar, Minoti V. Apte … (1984)

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Author and article information

Journal

Journal ID (nlm-ta): Perspect Clin Res

Journal ID (iso-abbrev): Perspect Clin Res

Journal ID (publisher-id): PCR

Title: Perspectives in Clinical Research

Publisher: Medknow Publications & Media Pvt Ltd (India )

ISSN (Print): 2229-3485

ISSN (Electronic): 2229-5488

Publication date (Print): Jan-Mar 2017

Volume: 8

Issue: 1

Pages: 37-40

Affiliations

[1 ]Scientific Advisory Committee, Hinduja Hospital, Mumbai, Maharashtra, India

[2 ]Scientific Advisory Committee, KEM Hospital, Pune, Maharashtra, India

Author notes

Address for correspondence: Dr. Arun S. Nanivadekar, 201, Avalon, Raheja Acropolis 1, Deonar, Mumbai - 400 088, Maharashtra, India. E-mail: arunn@ 123456vsnl.com

Article

Publisher ID: PCR-8-37

DOI: 10.4103/2229-3485.198547

PMC ID: 5299803

SO-VID: 050ea756-1a87-4158-ac50-e8da734003c0

License:

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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