Sample size calculation in medical studies.

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Abstract

Optimum sample size is an essential component of any research. The main purpose of the sample size calculation is to determine the number of samples needed to detect significant changes in clinical parameters, treatment effects or associations after data gathering. It is not uncommon for studies to be underpowered and thereby fail to detect the existing treatment effects due to inadequate sample size. In this paper, we explain briefly the basic principles of sample size calculations in medical studies.

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Journal

Journal ID (iso-abbrev): Gastroenterol Hepatol Bed Bench

Title: Gastroenterology and hepatology from bed to bench

Publisher:

ISSN: 2008-2258

ISSN (Print): 2008-2258

Publication date (Electronic): 2013

Volume: 6

Issue: 1

Affiliations

[1 ] Department of Biostatistics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

[2 ] Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

[3 ] Alborz University of Medical Sciences, Karaj, Iran.

Article

PMC ID: 4017493

PubMed ID: 24834239

SO-VID: a55b81cb-77d3-4261-9e96-3922a680ef19

History

Keywords: Medical studies,Sample size

Data availability:

Keywords: Medical studies, Sample size

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