Computational epistasis by Markus Hoffmann

Articles on the relationship of epistasis to bioinformatics and how scientists have developed computational tools to identify and analyse epistasis.

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Epistasis is a phenomenon in genetics in which the effect of a gene mutation is dependent on the presence or absence of mutations in one or more other genes, respectively termed modifier genes. In other words, the effect of the mutation is dependent on the genetic background in which it appears.

https://en.wikipedia.org/wiki/Epistasis

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Markus Hoffmann

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Main image credit:	https://en.wikipedia.org/wiki/Epistasis
Background image credit:	https://www.genetics.org/content/212/1/245.figures-only
ScienceOpen disciplines:	Applied computer science, Computer science, Neural & Evolutionary computing, Bioinformatics & Computational biology
Keywords:	epistasis, mutation, computational complexity, genome, SNP
DOI:	10.14293/S2199-1006.1.SOR-COMPSCI.CL8U8DK.v1

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