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      Organization in Biology 

      Organisms: Between a Kantian Approach and a Liberal Approach

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      Springer International Publishing

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          Abstract

          The concept of “organism” has been central to modern biology, with its definition and philosophical implications evolving since the nineteenth century. In contemporary biology, the divide between developmental and physiological approaches and evolutionary approaches has influenced the definition of organism. The convergence between molecular biology and evolutionary biology has led to the term “suborganismal biology,” while the return to the organism has been characterized by animal behavior studies and Evo-devo. The philosophical approach to the concept of individual is divided between a Kantian understanding of organism, which defines necessary and sufficient conditions for any X to be a “natural purpose,” and an evolutionary approach, which considers what a biological individual is and confers natural selection a key role in this definition. While the former aims to find necessary and sufficient conditions for an organism, the latter thinks in terms of conceptual spaces, being much more liberal in pointing out organisms in the world. The paper examines possible connections between these two approaches and assesses the prospects of a reconciliation between them.

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          Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics

          The term apoptosis is proposed for a hitherto little recognized mechanism of controlled cell deletion, which appears to play a complementary but opposite role to mitosis in the regulation of animal cell populations. Its morphological features suggest that it is an active, inherently programmed phenomenon, and it has been shown that it can be initiated or inhibited by a variety of environmental stimuli, both physiological and pathological. The structural changes take place in two discrete stages. The first comprises nuclear and cytoplasmic condensation and breaking up of the cell into a number of membrane-bound, ultrastructurally well-preserved fragments. In the second stage these apoptotic bodies are shed from epithelial-lined surfaces or are taken up by other cells, where they undergo a series of changes resembling in vitro autolysis within phagosomes, and are rapidly degraded by lysosomal enzymes derived from the ingesting cells. Apoptosis seems to be involved in cell turnover in many healthy adult tissues and is responsible for focal elimination of cells during normal embryonic development. It occurs spontaneously in untreated malignant neoplasms, and participates in at least some types of therapeutically induced tumour regression. It is implicated in both physiological involution and atrophy of various tissues and organs. It can also be triggered by noxious agents, both in the embryo and adult animal. Images Fig. 8-10 Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 6 Fig. 7 Fig. 11-14 Fig. 15-18 Fig. 19 Fig. 20-22 Fig. 23 and 24
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            The genetical evolution of social behaviour. I.

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              Concluding Remarks

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                Author and book information

                Book Chapter
                2024
                November 11 2023
                : 127-157
                10.1007/978-3-031-38968-9_7
                2abc98b2-f2a4-4a9e-96a0-f764a06fce00
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