In dynamic environments it must be possible to quickly implement new business processes, to enable ad-hoc deviations from the defined business processes on-demand (e.g., by dynamically adding, deleting or moving process activities), and to support dynamic process evolution (i.e., to propagate process schema changes to already running process instances). These fundamental requirements must be met without affecting process consistency and robustness of the process-aware information system. In this chapter the authors describe how these challenges have been addressed in the ADEPT2 process management system. Their overall vision is to provide a next generation technology for the support of dynamic processes, which enables full process lifecycle management and which can be applied to a variety of application domains.