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      Which individual, social and environmental influences shape key phases in the amphetamine type stimulant use trajectory? A systematic narrative review and thematic synthesis of the qualitative literature

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          Abstract

          Background and aims

          There is limited evidence on what shapes amphetamine‐type stimulant (ATS) use trajectories. This systematic narrative review and qualitative synthesis aimed to identify individual, social and environmental influences shaping key phases in the ATS use trajectory: initiation, continuation, increase/relapse and decrease/abstinence.

          Methods

          MEDLINE, PsycINFO, EMBASE, and PROQUEST (social science premium collection) were searched from 2000 to 2018. Studies of any qualitative design were eligible for inclusion. Extracted data were analysed according to four key phases within drug pathways, and then cross‐analysed for individual, social and environmental influences.

          Results

          Forty‐four papers based on 39 unique studies were included, reporting the views of 1879 ATS users. Participants were aged 14–58 years, from varied socio‐economic and demographic groups, and located in North America, Europe, Australasia and South East Asia. Reasons for initiation included: to boost performance at work and in sexual relationships, promote a sense of social ‘belonging’ and help manage stress. Similar reasons motivated continued use, combined with the challenge of managing withdrawal effects in long‐term users. Increased tolerance and/or experiencing a critical life event contributed to an increase in use. Reasons for decrease focused on: increased awareness of the negative health impacts of long‐term use, disconnecting from social networks or relationships and financial instability.

          Conclusions

          Amphetamine‐type stimulant users are a highly diverse population, and their drug use careers are shaped by a complex dynamic of individual, social and environmental factors. Tailored, joined‐up interventions are needed to address users’ overlapping economic, health and social care needs in order to support long‐term abstinence.

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          Most cited references82

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          Methamphetamine: an update on epidemiology, pharmacology, clinical phenomenology, and treatment literature.

          Despite initial reports of a decline in use in the early 2000s, methamphetamine remains a significant public health concern with known neurotoxic and neurocognitive effects to the user. The goal of this review is to update the literature on methamphetamine use and addiction since its assent to peak popularity in 1990s.
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            Mental disorders as risk factors for substance use, abuse and dependence: results from the 10-year follow-up of the National Comorbidity Survey.

            The comorbidity of mental disorders and substance dependence is well documented, but prospective investigations in community samples are rare. This investigation examines the role of primary mental disorders as risk factors for the later onset of nicotine, alcohol and illicit drug use, abuse and dependence with abuse. The National Comorbidity Survey (NCS) was a nationally representative survey of mental and substance disorders in the United States carried out in 1990-92. The NCS-2 re-interviewed a probability subsample of NCS respondents in 2001-03, a decade after the baseline survey. A total of 5001 NCS respondents were re-interviewed in the NCS-2 (87.6% of baseline sample). Aggregate analyses demonstrated significant prospective risks posed by baseline mental disorders for the onset of nicotine, alcohol and illicit drug dependence with abuse over the follow-up period. Particularly strong and consistent associations were observed for behavioral disorders and previous substance use conditions, as well as for certain mood and anxiety disorders. Conditional analyses demonstrated that many observed associations were limited to specific categories of use, abuse or dependence, including several mental disorders that were non-significant predictors in the aggregate analyses. Many mental disorders are associated with an increased risk of later substance use conditions, but important differences in these associations are observed across the categories of use, abuse and dependence with abuse. These prospective findings have implications for the precision of prevention and treatment strategies targeting substance use disorders.
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              Finding qualitative research: an evaluation of search strategies

              Background Qualitative research makes an important contribution to our understanding of health and healthcare. However, qualitative evidence can be difficult to search for and identify, and the effectiveness of different types of search strategies is unknown. Methods Three search strategies for qualitative research in the example area of support for breast-feeding were evaluated using six electronic bibliographic databases. The strategies were based on using thesaurus terms, free-text terms and broad-based terms. These strategies were combined with recognised search terms for support for breast-feeding previously used in a Cochrane review. For each strategy, we evaluated the recall (potentially relevant records found) and precision (actually relevant records found). Results A total yield of 7420 potentially relevant records was retrieved by the three strategies combined. Of these, 262 were judged relevant. Using one strategy alone would miss relevant records. The broad-based strategy had the highest recall and the thesaurus strategy the highest precision. Precision was generally poor: 96% of records initially identified as potentially relevant were deemed irrelevant. Searching for qualitative research involves trade-offs between recall and precision. Conclusions These findings confirm that strategies that attempt to maximise the number of potentially relevant records found are likely to result in a large number of false positives. The findings also suggest that a range of search terms is required to optimise searching for qualitative evidence. This underlines the problems of current methods for indexing qualitative research in bibliographic databases and indicates where improvements need to be made.
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                Author and article information

                Contributors
                amy.odonnell@newcastle.ac.uk
                Journal
                Addiction
                Addiction
                10.1111/(ISSN)1360-0443
                ADD
                Addiction (Abingdon, England)
                John Wiley and Sons Inc. (Hoboken )
                0965-2140
                1360-0443
                12 October 2018
                January 2019
                : 114
                : 1 ( doiID: 10.1111/add.v114.1 )
                : 24-47
                Affiliations
                [ 1 ] Institute of Health and Society Newcastle University Newcastle upon Tyne UK
                [ 2 ] Centre of Interdisciplinary Addiction Research of Hamburg University, Department of Psychiatry University Medical Centre Hamburg‐Eppendorf Hamburg Germany
                Author notes
                [*] [* ] Correspondence to: Amy O'Donnell, Institute of Health and Society, Newcastle University, Baddiley‐Clark Building, Richardson Road, Newcastle upon Tyne NE2 4AX, UK. E‐mail: amy.odonnell@ 123456newcastle.ac.uk
                Author information
                http://orcid.org/0000-0003-4071-9434
                Article
                ADD14434 ADD-18-0289.R2
                10.1111/add.14434
                6519251
                30176077
                31425f37-e745-4260-9102-db0a7d86a63b
                © 2018 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 28 March 2018
                : 04 June 2018
                : 24 August 2018
                Page count
                Figures: 2, Tables: 4, Pages: 24, Words: 3898
                Funding
                Funded by: Department of Health
                Award ID: ATTUNE: Understanding the pathways for stimulant u
                Categories
                Review
                Review
                Custom metadata
                2.0
                add14434
                January 2019
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.6.2.1 mode:remove_FC converted:15.05.2019

                Clinical Psychology & Psychiatry
                amphetamine‐related disorders,amphetamine‐type stimulants,drug use trajectory,life course,qualitative synthesis,systematic review

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